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本文引用的文献

1
Variation in susceptibility of mouse strains to Leishmania donovani infection.小鼠品系对杜氏利什曼原虫感染易感性的差异。
Trans R Soc Trop Med Hyg. 1972;66(4):527-8.
2
Letter: Genetic control of natural resistance to Leishmania donovani.信件：对杜氏利什曼原虫天然抗性的遗传控制。
Nature. 1974 Jul 26;250(464):353-4. doi: 10.1038/250353a0.
3
Natural resistance to Salmonella infection, delayed hypersensitivity and Ir genes in different strains of mice.不同品系小鼠对沙门氏菌感染的天然抵抗力、迟发型超敏反应和免疫应答基因
Nature. 1974 Mar 22;248(446):345-7. doi: 10.1038/248345a0.
4
Histocompatibility-linked immune response genes.组织相容性连锁免疫反应基因
Science. 1972 Jan 21;175(4019):273-9. doi: 10.1126/science.175.4019.273.
5
Genetics of resistance to infection with Salmonella typhimurium in mice.小鼠对鼠伤寒沙门氏菌感染的抗性遗传学
J Infect Dis. 1976 Jan;133(1):72-8. doi: 10.1093/infdis/133.1.72.
6
Heightened resistance of athymic, nude (nu/nu) mice to experimental Pseudomonas aeruginosa ocular infection.无胸腺裸鼠（nu/nu）对实验性铜绿假单胞菌眼部感染的抵抗力增强。
Infect Immun. 1978 Dec;22(3):926-33. doi: 10.1128/iai.22.3.926-933.1978.
7
Host defenses in experimental scrub typhus: genetics of natural resistance to infection.实验性恙虫病中的宿主防御：对感染的天然抵抗力的遗传学
Infect Immun. 1978 Feb;19(2):583-8. doi: 10.1128/iai.19.2.583-588.1978.
8
Resistance and susceptibility of mice to bacterial infection: genetics of listeriosis.小鼠对细菌感染的抗性与易感性：李斯特菌病的遗传学
Infect Immun. 1978 Mar;19(3):755-62. doi: 10.1128/iai.19.3.755-762.1978.
9
Influence of genetic factors on natural resistance of mice to Pseudomonas aeruginosa.遗传因素对小鼠对铜绿假单胞菌天然抵抗力的影响。
J Infect Dis. 1979 Apr;139(4):396-400. doi: 10.1093/infdis/139.4.396.

小鼠角膜对铜绿假单胞菌反应的遗传控制

Genetic control of the murine corneal response to Pseudomonas aeruginosa.

作者信息

Berk R S, Leon M A, Hazlett L D

出版信息

Infect Immun. 1979 Dec;26(3):1221-3. doi: 10.1128/iai.26.3.1221-1223.1979.

DOI:10.1128/iai.26.3.1221-1223.1979
PMID:528054
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC414751/
Abstract

Inbred mouse strains differ in susceptibility to intracorneal challenge with Pseudomonas aeruginosa. Genetic studies indicate that resistance to corneal infection is dominant over susceptibility and is controlled by autosomal genes, at least one of which is located outside of the H-2 locus. On the basis of genetic complementation studies, the susceptible strains BALB/c and C57BL/6 each bear one resistance gene, since the F1 hybrid (BALB/c X C57BL/6) was uniformly resistant to infection.

摘要

近交系小鼠品系对铜绿假单胞菌角膜内攻击的易感性存在差异。遗传学研究表明，对角膜感染的抗性对易感性呈显性，且由常染色体基因控制，其中至少有一个基因位于H-2基因座之外。基于遗传互补研究，易感品系BALB/c和C57BL/6各自携带一个抗性基因，因为F1杂种（BALB/c×C57BL/6）对感染具有一致的抗性。