担子菌纲真菌产生的抗生素。IX. 奥德曼菌素，一种从黏奥德蘑（Schrader ex Fr.）Hoehnel（伞菌目）中提取的抗真菌抗生素。
Antibiotics from basidiomycetes. IX. Oudemansin, an antifungal antibiotic from Oudemansiella mucida (Schrader ex Fr.) Hoehnel (Agaricales).
作者信息
Anke T, Hecht H J, Schramm G, Steglich W
出版信息
J Antibiot (Tokyo). 1979 Nov;32(11):1112-7. doi: 10.7164/antibiotics.32.1112.
PMID:528381
Abstract
From mycelial cultures of Oudemansiella mucida a crystalline optically active antibiotic, oudemansin (2), has been isolated; its structure is closely related to strobilurin A (1). The relative configuration of oudemansin have been determined by X-ray analysis. The antibiotic exhibits strong antifungal properties and inhibits respiration in fungi, cells of the ascitic form of EHRLICH carcinoma, and rat liver mitochondria.
摘要
从粘液奥德蘑的菌丝体培养物中分离出一种结晶性光学活性抗生素——奥德菌素（2）；其结构与嗜球果伞素A（1）密切相关。奥德菌素的相对构型已通过X射线分析确定。该抗生素具有很强的抗真菌特性，能抑制真菌、艾氏腹水癌腹水形式的细胞以及大鼠肝线粒体的呼吸作用。
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