海拉细胞信使核糖核酸中富含腺苷酸的序列及其与DNA中重复位点的可能关系。
An adenylic acid-rich sequence in messenger RNA of HeLa cells and its possible relationship to reiterated sites in DNA.
作者信息
Darnell J E, Wall R, Tushinski R J
出版信息
Proc Natl Acad Sci U S A. 1971 Jun;68(6):1321-5. doi: 10.1073/pnas.68.6.1321.
Abstract
Messenger RNA from HeLa cells contains, as part of the polynucleotide chain, RNase-resistant sequences that are labeled by adenosine but not by uridine. Heterogeneous nuclear RNA also contains adenylate-rich RNase-resistant regions, but in lower proportion than messenger RNA. Hybridization to DNA of (32)P-labeled messenger RNA reveals that some of the adenylate-rich region is included in the rapidly-hybridizing fraction.
摘要
来自海拉细胞的信使核糖核酸作为多核苷酸链的一部分，含有对核糖核酸酶有抗性的序列，这些序列能用腺苷标记，但不能用尿苷标记。不均一核核糖核酸也含有富含腺苷酸的对核糖核酸酶有抗性的区域，但其比例低于信使核糖核酸。用（32）P标记的信使核糖核酸与脱氧核糖核酸杂交显示，一些富含腺苷酸的区域包含在快速杂交部分中。
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