结核病根除的流行病学基础。3. 人类和牛感染后患肺结核的风险。
Epidemiological basis of tuberculosis eradication. 3. Risk of pulmonary tuberculosis after human and bovine infection.
作者信息
Magnus K
出版信息
Bull World Health Organ. 1966;35(4):483-508.
Abstract
Cattle tuberculosis was eradicated in Denmark more than 10 years ago, but still a sizable proportion of Danish tuberculin reactors owe their sensitivity to tuberculous infection derived from bovine sources. This paper deals with the question whether the risk of pulmonary tuberculosis after such infection is different from that after tuberculous infection acquired from man. This problem has been studied by utilizing data from the Danish tuberculosis mass campaign, 1950-52, including eight years of follow-up, and data from the eradication programme for cattle tuberculosis. It is shown that the tuberculin reactors can be divided into two groups carrying a widely different risk of late pulmonary tuberculosis: one, infected from bovine sources, carrying a low risk; the other, infected from human sources, carrying a relatively high risk.
摘要
十多年前丹麦就已根除牛结核病，但仍有相当一部分丹麦结核菌素反应者的敏感性归因于源自牛源的结核感染。本文探讨了这种感染后发生肺结核的风险是否与人类感染结核后不同的问题。通过利用1950 - 1952年丹麦结核病大规模防治运动的数据（包括八年随访）以及牛结核病根除计划的数据对这一问题进行了研究。结果表明，结核菌素反应者可分为两组，发生晚期肺结核的风险差异很大：一组是牛源感染，风险较低；另一组是人类感染源，风险相对较高。
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