Mikaeloff P, Amouroux C, Boivin F, Loire R, Vialle C, Guidollet G, Coullet P, Van Haecke P, Bouillot A, Karo G
Nouv Presse Med. 1979 Dec 24;8(50):4105-7.
A technique of myocardial protection using a perfusion circuit in deep hypothermia via the ascending aorta or by selective cannulation of the coronaries has been used over a period of 2 years in almost 200 patients undergoing surgery requiring prolonged aortic clamping. It ensures rapid and homogeneous cooling of the myocardium (10-12 degrees C) and meets its reduced oxygen needs. It may be completed by cardioplegia (infusion of potassium chloride or lidocaine using an automatic syringe at a determined level). This simple technique permits a rapid spontaneous return of normal effective cardiac action. No low cardiac output syndromes have been seen since it has been used. Laboratory, histological, biochemical and haemodynamic studies carried out have confirmed its harmless nature.
一种在深低温下通过升主动脉或选择性冠状动脉插管使用灌注回路进行心肌保护的技术，已在近两年时间里应用于近200例需要长时间主动脉阻断的手术患者。它能确保心肌快速均匀冷却至（10 - 12摄氏度），并满足其降低的氧需求。可通过心脏停搏液（使用自动注射器在特定水平输注氯化钾或利多卡因）来完善该技术。这种简单的技术能使心脏快速自发恢复正常有效的活动。自使用该技术以来，未出现低心排血量综合征。所进行的实验室、组织学、生化和血流动力学研究均证实了其无害性。
