脂多糖质量对肠炎沙门氏菌小鼠毒力的影响。
Effect of the quality of the lipopolysaccharide on mouse virulence of Salmonella enteritidis.
作者信息
Valtonen M V, Plosila M, Valtonen V V, Mäkelä P H
出版信息
Infect Immun. 1975 Oct;12(4):828-32. doi: 10.1128/iai.12.4.828-832.1975.
Abstract
The cell wall O antigen is known to affect mouse virulence of Salmonella. We have shown earlier that S. typhimurium expressing somatic antigen 9,12 is less virulent than its 4,12 sister transductants in mice after intraperitoneal inoculation, suggesting that the 4,12-type O antigen is connected with high virulence in mice. In this report we show, in accord with this suggestion, that when the naturally occurring O-9,12 S. enteritidis is made O-4,12 by transduction, its virulence is increased. The difference between O-9,12 and O-4,12 sister transductants is highly significant, with P less than 0.001.
摘要
已知细胞壁O抗原会影响沙门氏菌对小鼠的毒力。我们之前已经表明，表达菌体抗原9,12的鼠伤寒沙门氏菌在腹腔接种后对小鼠的毒力低于其4,12型姐妹转导子，这表明4,12型O抗原与小鼠的高毒力相关。在本报告中，与这一推测一致，我们发现当通过转导使天然存在的O-9,12肠炎沙门氏菌变为O-4,12型时，其毒力会增加。O-9,12和O-4,12型姐妹转导子之间的差异非常显著，P值小于0.001。
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1
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Virology. 1967 Feb;31(2):207-16. doi: 10.1016/0042-6822(67)90164-x.
2
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Eur J Biochem. 1971 Oct 26;22(4):500-5. doi: 10.1111/j.1432-1033.1971.tb01569.x.
3
Mouse virulence of Salmonella strains: the effect of different smooth-type O side-chains.沙门氏菌菌株的小鼠毒力：不同光滑型O侧链的影响。
J Gen Microbiol. 1970 Dec;64(3):255-68. doi: 10.1099/00221287-64-3-255.
4
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6
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J Infect Dis. 1973 Jul;128:Suppl:81-5. doi: 10.1093/infdis/128.supplement_1.s81.
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