Karthigasu K, Reade P C, Jenkin C R
Immunology. 1965 Jul;9(1):67-73.
The bactericidal capacity of the fixed macrophages of foetal and neonatal rats and chicks was investigated. It has been shown that as a population the phagocytic cells of these embryos lack a bactericidal mechanism for certain strains of Gram-negative bacteria, even in the presence of specific antibody. Neonates, however, were shown to have developed such a mechanism soon after birth. The implication of these findings is discussed in relation to antibody formation.
对胎儿及新生大鼠和雏鸡的固定巨噬细胞的杀菌能力进行了研究。结果表明,作为一个群体,这些胚胎的吞噬细胞对某些革兰氏阴性菌菌株缺乏杀菌机制,即使存在特异性抗体也是如此。然而,新生动物在出生后不久就显示出已形成了这样一种机制。结合抗体形成对这些发现的意义进行了讨论。