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Suppression of radiation sensitivity and capsular polysaccharide synthesis in Escherichia coli K-12 by ochre suppressors.赭石抑制基因对大肠杆菌K-12辐射敏感性和荚膜多糖合成的抑制作用
J Bacteriol. 1967 Aug;94(2):388-95. doi: 10.1128/jb.94.2.388-395.1967.
2
Mutation preventing capsular polysaccharide synthesis in Escherichia coli K-12 and its effect on bacteriophage resistance.阻止大肠杆菌K-12中荚膜多糖合成的突变及其对噬菌体抗性的影响。
J Bacteriol. 1971 May;106(2):432-7. doi: 10.1128/jb.106.2.432-437.1971.
3
Cloning of Escherichia coli DNA that controls cell division and capsular polysaccharide synthesis.控制大肠杆菌细胞分裂和荚膜多糖合成的DNA克隆。
Proc Natl Acad Sci U S A. 1976 Mar;73(3):697-701. doi: 10.1073/pnas.73.3.697.
4
Derepression of phosphomannose isomerase by regulator gene mutations involved in capsular polysaccharide synthesis in Escherichia coli K-12.大肠杆菌K-12中参与荚膜多糖合成的调节基因突变导致磷酸甘露糖异构酶的去阻遏。
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5
P1-mediated transduction of a gene that controls radiation sensitivity and capsular polysaccharide synthesis from Shigella dysenteriae to Escherichia coli.P1介导的从痢疾志贺氏菌到大肠杆菌的一个控制辐射敏感性和荚膜多糖合成的基因的转导。
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[Genetic characteristics of levomycetin-resistant strains of E. coli K-12 with disturbed synthesis of capsule polysaccharide].
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Identification of the gene lon (capR) product as a 94-kilodalton polypeptide by cloning and deletion analysis.通过克隆和缺失分析鉴定基因lon（capR）产物为一种94千道尔顿的多肽。
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Depression of guanosine diphosphate-mannose pyrophosphorylase by mutations in two different regulator genes involved in capsular polysaccharide synthesis in Escherichia coli K-12.大肠杆菌K-12中参与荚膜多糖合成的两个不同调节基因突变导致鸟苷二磷酸甘露糖焦磷酸化酶活性降低。
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Multiple regulator gene control of the galactose operon in Escherichia coli K-12.大肠杆菌K-12中半乳糖操纵子的多调节基因控制
J Bacteriol. 1972 Jun;110(3):1089-99. doi: 10.1128/jb.110.3.1089-1099.1972.

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ATP hydrolysis-dependent protease activity of the lon (capR) protein of Escherichia coli K-12.大肠杆菌K-12的lon（capR）蛋白的ATP水解依赖性蛋白酶活性。
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2
Regulation of cell division in Escherichia coli: SOS induction and cellular location of the sulA protein, a key to lon-associated filamentation and death.大肠杆菌中细胞分裂的调控：SOS 诱导与 sulA 蛋白的细胞定位，lon 相关丝状化和死亡的关键因素
J Bacteriol. 1984 May;158(2):551-61. doi: 10.1128/jb.158.2.551-561.1984.
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Cloning of gene lon (capR) of Escherichia coli K-12 and identification of polypeptides specified by the cloned deoxyribonucleic acid fragment.大肠杆菌K-12基因lon（capR）的克隆及克隆的脱氧核糖核酸片段所指定的多肽的鉴定。
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Colicin tolerance induced by ampicillin or mutation to ampicillin resistance in a strain of Escherichia coli K-12.氨苄青霉素诱导的大肠杆菌K - 12菌株对大肠杆菌素的耐受性或对氨苄青霉素抗性的突变。
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6
Depression of guanosine diphosphate-mannose pyrophosphorylase by mutations in two different regulator genes involved in capsular polysaccharide synthesis in Escherichia coli K-12.大肠杆菌K-12中参与荚膜多糖合成的两个不同调节基因突变导致鸟苷二磷酸甘露糖焦磷酸化酶活性降低。
J Bacteriol. 1970 Mar;101(3):965-72. doi: 10.1128/jb.101.3.965-972.1970.
7
Control of uridine diphosphate-glucose dehydrogenase synthesis and uridine diphosphate-glucuronic acid accumulation by a regulator gene mutation in Escherichia coli K-12.大肠杆菌K-12中调节基因突变对尿苷二磷酸葡萄糖脱氢酶合成及尿苷二磷酸葡萄糖醛酸积累的控制
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8
Dominance of ultraviolet radiation resistance in partial diploids of Escherichia coli K-12.大肠杆菌K-12部分二倍体中紫外线抗性的显性
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9
Locus for radiation resistance in Escherichia coli strain B-r.大肠杆菌B-r菌株中抗辐射位点
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10
Genetic analysis of lon mutants of strain K-12 of Escherichia coli.大肠杆菌K-12菌株lon突变体的遗传分析。
Mol Gen Genet. 1968;103(2):105-15. doi: 10.1007/BF00427138.

本文引用的文献

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Suppression in vitro: Identification of a Serine-sRNA as a "Nonsense" Suppressor.体外抑制：鉴定一种丝氨酸-sRNA 作为“无意义”抑制物。
Science. 1965 Jul 23;149(3682):417-22. doi: 10.1126/science.149.3682.417.
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Isolation of the lac repressor.乳糖阻遏蛋白的分离
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AMINO ACID SUBSTITUTIONS RESULTING FROM SUPPRESSION OF NONSENSE MUTATIONS. I. SERINE INSERTION BY THE SU-1 SUPPRESSOR GENE.由无义突变抑制导致的氨基酸替换。一、SU-1 抑制基因导致的丝氨酸插入
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PLEIOTROPIC EFFECTS OF SUPPRESSORS OF A LAC-"OPERATOR NEGATIVE" MUTATION IN ESCHERICHIA COLI.大肠杆菌中乳糖操纵子“负”突变抑制子的多效性效应
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POSTIRRADIATION GROWTH, DIVISION, AND RECOVERY IN BACTERIA.细菌辐射后的生长、分裂与恢复
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ISOLATION OF A PROTEIN SPECIFIED BY A REGULATOR GENE.调节基因所指定蛋白质的分离
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ANALYSIS OF A GENE CONTROLLING CELL DIVISION AND SENSITIVITY TO RADIATION IN ESCHERICHIA COLI.大肠杆菌中一个控制细胞分裂及辐射敏感性的基因分析
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REGULATORY MECHANISMS FOR SYNTHESIS OF CAPSULAR POLYSACCHARIDE IN MUCOID MUTANTS OF ESCHERICHIA COLI K12.大肠杆菌K12黏液突变体中荚膜多糖合成的调控机制
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CO-LINEARITY OF THE GENE WITH THE POLYPEPTIDE CHAIN.基因与多肽链的共线性
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赭石抑制基因对大肠杆菌K-12辐射敏感性和荚膜多糖合成的抑制作用

Suppression of radiation sensitivity and capsular polysaccharide synthesis in Escherichia coli K-12 by ochre suppressors.

作者信息

Markovitz A, Baker B

出版信息

J Bacteriol. 1967 Aug;94(2):388-95. doi: 10.1128/jb.94.2.388-395.1967.

DOI:10.1128/jb.94.2.388-395.1967
PMID:5341863
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC315052/
Abstract

A class of suppressors effective on nonsense polarity mutations suppresses several independent mutations in a gene (capR) that controls ultraviolet-radiation sensitivity and capsular polysaccharide synthesis. Since these ochre suppressors function at the level of translation of messenger ribonucleic acid into protein, the results provide evidence that the product of the capR gene is a protein.

摘要

一类对无义极性突变有效的抑制子可抑制控制紫外线辐射敏感性和荚膜多糖合成的基因（capR）中的几个独立突变。由于这些赭石型抑制子在信使核糖核酸翻译成蛋白质的水平上起作用，因此这些结果提供了证据，证明capR基因的产物是一种蛋白质。