Newhouse M L
Br J Ind Med. 1969 Oct;26(4):294-301. doi: 10.1136/oem.26.4.294.
294-301. A cohort study of over 4,500 male workers employed at an asbestos factory making both textiles and insulation materials is described. The main analysis of the mortality of workers employed between April 1, 1933, the date of the implementation of the Asbestos Regulations, and May 1, 1964. The analysis was made in relation to job, length of exposure, and length of follow-up after first exposure. There was no significant difference between the number of deaths occurring in the factory population and the national figures, until an interval of 16 years or longer had elapsed from first exposure in the factory. There were 1,160 men who fulfilled this criterion. In this group there was no excess mortality among those who worked in jobs where exposure was low or moderate, but among those with jobs which entailed heavy exposure there was a significant excess of deaths from cancer of the lung and pleura, and cancer of other sites, in men with a total period of employment in the factory of less than two years, as well as with those who worked for longer. Excess mortality from respiratory disease was observed only among severely exposed workers with long service.
294 - 301. 本文描述了一项对一家生产纺织品和绝缘材料的石棉工厂4500多名男性工人的队列研究。主要分析了1933年4月1日（《石棉条例》实施之日）至1964年5月1日期间受雇工人的死亡率。分析涉及工作岗位、接触时长以及首次接触后的随访时长。在工厂人群中发生的死亡人数与全国数据之间没有显著差异，直到从首次在工厂接触起经过16年或更长时间间隔。有1160名男性符合这一标准。在这一组中，从事低或中度接触工作的人没有超额死亡率，但在从事高接触工作的人中，在工厂总就业时长不到两年的男性以及工作更长时间者中，肺癌、胸膜癌和其他部位癌症的死亡人数显著超额。仅在长期从事高接触工作的工人中观察到呼吸系统疾病导致的超额死亡率。
