Kushmerick M J, Podolsky R J
Science. 1969 Dec 5;166(3910):1297-8. doi: 10.1126/science.166.3910.1297.
The diffusivities of ionic potassium, sodium, sulfate, and adenosine triphosphate inside a nmuscle cell are reduced by a factor of 2, relative to diffusivities in aqueous solution. The diffusion coefficients of nonelectrolytes are reduced by the same factor, showing that the diffusion of the ions is retarded by physical, rather than chemical, interactions. In contrast, the diffusivity of the calcium ion, which is taken up by the sarcoplasmic reticulum, is reduced fiftyfold.
相对于在水溶液中的扩散系数,肌肉细胞内离子钾、钠、硫酸根和三磷酸腺苷的扩散系数降低了2倍。非电解质的扩散系数也降低了相同倍数,这表明离子的扩散是受到物理相互作用而非化学相互作用的阻碍。相比之下,被肌浆网摄取的钙离子的扩散系数降低了50倍。