Merdinger E, Guthmann W S, Mangine F W
Appl Microbiol. 1969 Sep;18(3):365-8. doi: 10.1128/am.18.3.365-368.1969.
The inhibitory effects of three topical anesthetics of various concentrations on the growth of Pullularia pullulans, Debaryomyces hansenii, and on pigment production by P. pullulans were investigated. The topical anesthetics were benoxinate hydrochloride, proparacaine hydrochloride, and tetracaine hydrochloride. In decreasing order, the inhibiting effects of the drugs on growth were benoxinate, tetracaine, and proparacaine for P. pullulans, and tetracaine, benoxinate, and proparacaine for D. hansenii. The pigment formation in P. pullulans was inhibited by the three drugs.
研究了三种不同浓度的局部麻醉剂对出芽短梗霉、汉逊德巴利酵母生长以及出芽短梗霉色素产生的抑制作用。局部麻醉剂为盐酸丁氧普鲁卡因、盐酸丙美卡因和盐酸丁卡因。三种药物对出芽短梗霉生长的抑制作用从强到弱依次为丁氧普鲁卡因、丁卡因、丙美卡因；对汉逊德巴利酵母生长的抑制作用从强到弱依次为丁卡因、丁氧普鲁卡因、丙美卡因。这三种药物均抑制了出芽短梗霉色素的形成。
