Holland J J, Kiehn E D
Science. 1970 Jan 9;167(3915):202-5. doi: 10.1126/science.167.3915.202.
During infection by influenza virus, viral proteins become firmly attached to (or part of) host cell plasma membrane, nuclear membranes, mitochondrial, and microsomal membranes. Purified virus particles contain less than I percent host cell protein. Virus envelope proteins completely replace host membrane proteins in those discrete spots on the plasma membrane from which progeny virions bud out.
在流感病毒感染期间,病毒蛋白会牢固地附着于(或成为其一部分)宿主细胞质膜、核膜、线粒体膜和微粒体膜。纯化的病毒颗粒所含宿主细胞蛋白不到1%。病毒包膜蛋白在质膜上子代病毒粒子出芽的离散位点完全取代宿主膜蛋白。