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1
Studies on the pathogenesis of fever. XVII. The cationic control of pyrogen release from exudate granulocytes in vitro.发热发病机制的研究。十七。体外渗出性粒细胞中热原释放的阳离子控制。
J Exp Med. 1970 Jan 1;131(1):165-78. doi: 10.1084/jem.131.1.165.
2
Studies on the pathogenesis of fever. XX. Suppression and regeneration of pyrogen-producing capacity of exudate granulocytes.发热发病机制的研究。XX. 渗出性粒细胞产热能力的抑制与再生
J Exp Med. 1970 Jul 1;132(1):127-33. doi: 10.1084/jem.132.1.127.
3
Studies on the pathogenesis of fever. 18. Activation of leukocytes for pyrogen production.发热的发病机制研究。18. 白细胞产热原的激活。
J Exp Med. 1970 Jan 1;131(1):179-88. doi: 10.1084/jem.131.1.179.
4
STUDIES ON THE PATHOGENESIS OF FEVER. 13. THE EFFECT OF PHAGOCYTOSIS ON THE RELEASE OF ENDOGENOUS PYROGEN BY POLYMORPHONUCLEAR LEUKOCYTES.发热的发病机制研究。13. 吞噬作用对多形核白细胞释放内源性致热原的影响。
J Exp Med. 1964 May 1;119(5):715-26. doi: 10.1084/jem.119.5.715.
5
Studies on the pathogenesis of fever. XIX. Localization of pyrogen in granulocytes.发热发病机制的研究。第十九部分。热原在粒细胞中的定位。
J Exp Med. 1970 Apr 1;131(4):701-9. doi: 10.1084/jem.131.4.701.
6
STUDIES ON THE PATHOGENESIS OF FEVER. XII. ELECTROLYTIC FACTORYS INFLUENCING THE RELEASE OF ENDOGENOUS PYROGEN FROM POLYMORPHONUCLEAR LEUKOCYTES.发热机制的研究。十二。影响多形核白细胞释放内源性致热原的电解因素。
J Exp Med. 1964 May 1;119(5):697-714. doi: 10.1084/jem.119.5.697.
7
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J Exp Med. 1970 Apr 1;131(4):727-43. doi: 10.1084/jem.131.4.727.
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Synthesis of endogenous pyrogen by rabbit leukocytes.兔白细胞内源性致热原的合成。
J Exp Med. 1973 May 1;137(5):1263-74. doi: 10.1084/jem.137.5.1263.
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[Mechanisms of release of leucocytic pyrogen].[白细胞致热原的释放机制]
Nihon Yakurigaku Zasshi. 1975 Apr;71(3):263-71. doi: 10.1254/fpj.71.263.
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Release of an endogenous pyrogen in vitro from rabbit mononuclear cells.兔单核细胞在体外释放内源性热原。
J Exp Med. 1967 Aug 1;126(2):357-84. doi: 10.1084/jem.126.2.357.

引用本文的文献

1
Studies on the pathogenesis of fever. XX. Suppression and regeneration of pyrogen-producing capacity of exudate granulocytes.发热发病机制的研究。XX. 渗出性粒细胞产热能力的抑制与再生
J Exp Med. 1970 Jul 1;132(1):127-33. doi: 10.1084/jem.132.1.127.
2
Studies on the pathogenesis of fever. XIX. Localization of pyrogen in granulocytes.发热发病机制的研究。第十九部分。热原在粒细胞中的定位。
J Exp Med. 1970 Apr 1;131(4):701-9. doi: 10.1084/jem.131.4.701.
3
Studies on the pathogenesis of fever. 18. Activation of leukocytes for pyrogen production.发热的发病机制研究。18. 白细胞产热原的激活。
J Exp Med. 1970 Jan 1;131(1):179-88. doi: 10.1084/jem.131.1.179.
4
Studies on the mechanism of endogenous pyrogen production. I. Investigation of new protein synthesis in stimulated human blood leucocytes.内源性致热原产生机制的研究。I. 对受刺激的人血白细胞中新蛋白质合成的研究。
Yale J Biol Med. 1970 Dec;43(3):145-63.
5
Studies on the production of endogenous pyrogen by rabbit monocytes: the role of calcium and cyclic nucleotides.兔单核细胞内源性致热原产生的研究：钙和环核苷酸的作用。
Yale J Biol Med. 1985 Mar-Apr;58(2):165-78.

本文引用的文献

1
Studies on the pathogensis of fever. IX. The production of endogenous pyrogen by polymorphonuclear leucocytes.发热的发病机制研究。IX. 多形核白细胞产生内源性致热原。
J Exp Med. 1962 Jan 1;115(1):27-36. doi: 10.1084/jem.115.1.27.
2
Studies on the pathogenesis of fever. X. The effect of certain enzyme inhibitors on the production and activity of leucocvtic pvrogen.发热发病机制的研究。十、某些酶抑制剂对白细胞致热原产生和活性的影响。
J Exp Med. 1962 Jan 1;115(1):37-47. doi: 10.1084/jem.115.1.37.
3
ENZYMATIC BASIS FOR ACTIVE TRANSPORT OF NA+ AND K+ ACROSS CELL MEMBRANE.钠离子和钾离子跨细胞膜主动运输的酶学基础
Physiol Rev. 1965 Jul;45:596-617. doi: 10.1152/physrev.1965.45.3.596.
4
STUDIES ON THE PATHOGENESIS OF FEVER. XII. ELECTROLYTIC FACTORYS INFLUENCING THE RELEASE OF ENDOGENOUS PYROGEN FROM POLYMORPHONUCLEAR LEUKOCYTES.发热机制的研究。十二。影响多形核白细胞释放内源性致热原的电解因素。
J Exp Med. 1964 May 1;119(5):697-714. doi: 10.1084/jem.119.5.697.
5
STUDIES ON THE PATHOGENESIS OF FEVER. 13. THE EFFECT OF PHAGOCYTOSIS ON THE RELEASE OF ENDOGENOUS PYROGEN BY POLYMORPHONUCLEAR LEUKOCYTES.发热的发病机制研究。13. 吞噬作用对多形核白细胞释放内源性致热原的影响。
J Exp Med. 1964 May 1;119(5):715-26. doi: 10.1084/jem.119.5.715.
6
Studies on the pathogenesis of fever. XI. Quantitative features of the febrile response to leucocytic pyrogen.发热发病机制的研究。十一、对白细胞致热原发热反应的定量特征
J Exp Med. 1963 Mar 1;117(3):349-64. doi: 10.1084/jem.117.3.349.
7
Studies on the pathogenesis of fever. VI. The interaction of leucocytes and endotoxin in vitro.发热的发病机制研究。VI. 白细胞与内毒素的体外相互作用。
J Exp Med. 1959 Dec 1;110(6):1005-16. doi: 10.1084/jem.110.6.1005.
8
Quantitative aspects of the release of leukocyte pyrogen from rabbit blood incubated with endotoxin.内毒素孵育兔血中白细胞致热原释放的定量研究
J Exp Med. 1967 Nov 1;126(5):763-81. doi: 10.1084/jem.126.5.763.
9
Studies on the pathogenesis of fever. XV. The production of endogenous pyrogen by peritoneal macrophages.发热发病机制的研究。十五、腹膜巨噬细胞产生内源性致热原。
J Exp Med. 1967 Aug 1;126(2):385-94. doi: 10.1084/jem.126.2.385.
10
Studies on the pathogenesis of fever. XVI. Purification and further chemical characterization of granulocytic pyrogen.发热发病机制的研究。十六、粒细胞热原的纯化及进一步化学特性分析
J Exp Med. 1968 Feb 1;127(2):341-57. doi: 10.1084/jem.127.2.341.

发热发病机制的研究。十七。体外渗出性粒细胞中热原释放的阳离子控制。

Studies on the pathogenesis of fever. XVII. The cationic control of pyrogen release from exudate granulocytes in vitro.

作者信息

Hahn H H, Cheuk S F, Moore D M, Wood W B

出版信息

J Exp Med. 1970 Jan 1;131(1):165-78. doi: 10.1084/jem.131.1.165.

DOI:10.1084/jem.131.1.165
PMID:5409945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2138762/
Abstract

Evidence has been presented that the release of active endogenous pyrogen from rabbit exudate granulocytes incubated in isotonic NaCl is a relatively prompt energy-dependent process that is preceded by a rise in intracellular pyrogen, and involves a rise in total intracellular cations and an increased permeability of the cell membranes, but does not require the synthesis of new proteins.

摘要

有证据表明，在等渗氯化钠中孵育的兔渗出粒细胞释放活性内源性热原是一个相对迅速的能量依赖性过程，该过程之前细胞内热原会增加，涉及细胞内总阳离子增加和细胞膜通透性增加，但不需要合成新蛋白质。