Hahn H H, Cheuk S F, Moore D M, Wood W B
J Exp Med. 1970 Jan 1;131(1):165-78. doi: 10.1084/jem.131.1.165.
Evidence has been presented that the release of active endogenous pyrogen from rabbit exudate granulocytes incubated in isotonic NaCl is a relatively prompt energy-dependent process that is preceded by a rise in intracellular pyrogen, and involves a rise in total intracellular cations and an increased permeability of the cell membranes, but does not require the synthesis of new proteins.
有证据表明,在等渗氯化钠中孵育的兔渗出粒细胞释放活性内源性热原是一个相对迅速的能量依赖性过程,该过程之前细胞内热原会增加,涉及细胞内总阳离子增加和细胞膜通透性增加,但不需要合成新蛋白质。