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发热发病机制的研究。十七。体外渗出性粒细胞中热原释放的阳离子控制。

Studies on the pathogenesis of fever. XVII. The cationic control of pyrogen release from exudate granulocytes in vitro.

作者信息

Hahn H H, Cheuk S F, Moore D M, Wood W B

出版信息

J Exp Med. 1970 Jan 1;131(1):165-78. doi: 10.1084/jem.131.1.165.

Abstract

Evidence has been presented that the release of active endogenous pyrogen from rabbit exudate granulocytes incubated in isotonic NaCl is a relatively prompt energy-dependent process that is preceded by a rise in intracellular pyrogen, and involves a rise in total intracellular cations and an increased permeability of the cell membranes, but does not require the synthesis of new proteins.

摘要

有证据表明,在等渗氯化钠中孵育的兔渗出粒细胞释放活性内源性热原是一个相对迅速的能量依赖性过程,该过程之前细胞内热原会增加,涉及细胞内总阳离子增加和细胞膜通透性增加,但不需要合成新蛋白质。

相似文献

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Studies on the origin of human leukocytic pyrogen.人类白细胞致热原的起源研究。
J Exp Med. 1970 Apr 1;131(4):727-43. doi: 10.1084/jem.131.4.727.
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Synthesis of endogenous pyrogen by rabbit leukocytes.兔白细胞内源性致热原的合成。
J Exp Med. 1973 May 1;137(5):1263-74. doi: 10.1084/jem.137.5.1263.
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[Mechanisms of release of leucocytic pyrogen].[白细胞致热原的释放机制]
Nihon Yakurigaku Zasshi. 1975 Apr;71(3):263-71. doi: 10.1254/fpj.71.263.

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