Thompson K M, Tobin J O
Br Med J. 1970 May 2;2(5704):264-6. doi: 10.1136/bmj.2.5704.264.
Rubella virus was isolated from the fetus or products of conception in 29 out of 32 cases (91%) terminated because of clinical maternal rubella proved or supported by laboratory findings in the first trimester of pregnancy. Virus was isolated from similar material from only 3 out of 19 (16%) other clinical cases of rubella in which the laboratory findings were inconclusive or against the diagnosis or in which no laboratory tests were done. Virus was found in the amniotic fluid if the fetus was infected and there was no evidence that the placenta was any real barrier to fetal infection.
在32例因孕期头三个月经实验室检查证实或支持的临床孕妇风疹而终止妊娠的病例中,有29例(91%)从胎儿或妊娠产物中分离出风疹病毒。在另外19例风疹临床病例中,只有3例(16%)从类似材料中分离出病毒,这些病例的实验室检查结果不明确或与诊断不符,或者未进行实验室检测。如果胎儿受到感染且没有证据表明胎盘对胎儿感染有任何实质性屏障作用,那么在羊水中就能发现病毒。