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骨髓集落:人血细胞孵育上清液在体外的刺激作用

Bone marrow colonies: stimulation in vitro by supernatant from incubated human blood cells.

作者信息

Chervenick P A, Boggs D R

出版信息

Science. 1970 Aug 14;169(3946):691-2. doi: 10.1126/science.169.3946.691.

DOI:10.1126/science.169.3946.691
PMID:5429904
Abstract

A substance which stimulates growth of granulocytic and mononuclear cell colonies from mouse and human bone marrow was produced by incubated human blood cells. It is resistant to heat and freezing and is not dialyzable. Intact irradiated and unirradiated cells had very little activity, and sonically disrupted cells had no activity. The addition of plasma or sonically disrupted cells to the cell supernatant decreased its activity.

摘要

通过培养人血细胞产生了一种能刺激小鼠和人骨髓中的粒细胞和单核细胞集落生长的物质。它耐热且耐冻,不可透析。完整的经辐照和未经辐照的细胞活性很低,经超声破碎的细胞则无活性。向细胞上清液中添加血浆或经超声破碎的细胞会降低其活性。

相似文献

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Bone marrow colonies: stimulation in vitro by supernatant from incubated human blood cells.骨髓集落:人血细胞孵育上清液在体外的刺激作用
Science. 1970 Aug 14;169(3946):691-2. doi: 10.1126/science.169.3946.691.
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Human leukemic cells: in vitro growth of colonies containing the Philadelphia (Ph) chromosome.人类白血病细胞:含费城(Ph)染色体的集落的体外生长
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Factors from mouse tissues stimulating colony growth of mouse bone marrow cells in vitro.来自小鼠组织的因子在体外刺激小鼠骨髓细胞的集落生长。
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Formation of eosinophilic-like granulocytic colonies by mouse bone marrow cells in vitro.小鼠骨髓细胞在体外形成嗜酸性粒细胞样粒细胞集落。
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Serum potentiation of granulocyte and macrophage colony formation in vitro.体外血清对粒细胞和巨噬细胞集落形成的增强作用。
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引用本文的文献

1
Antigenically distinct subpopulations of myeloid progenitor cells (CFU-GM) in human peripheral blood and marrow.人类外周血和骨髓中抗原性不同的髓系祖细胞亚群(CFU-GM)。
Proc Natl Acad Sci U S A. 1983 Jul;80(13):4114-8. doi: 10.1073/pnas.80.13.4114.
2
Identification of the colony-stimulating cell in human peripheral blood.人外周血中集落刺激细胞的鉴定。
J Clin Invest. 1972 Nov;51(11):2981-3. doi: 10.1172/JCI107124.
3
Regulatory mechanisms acting on hemopoietic stem cells. Some clinical implications.作用于造血干细胞的调控机制。一些临床意义。
Am J Pathol. 1971 Dec;65(3):601-19.
4
Colony formation in culture by bovine granulopoietic progenitor cells.牛粒细胞生成祖细胞在培养中的集落形成。
Can J Comp Med. 1974 Apr;38(2):145-52.
5
Lack of mitogenic effects of growth hormone on human leukemic lymphoblasts.生长激素对人白血病淋巴母细胞无促有丝分裂作用。
Eur J Pediatr. 1987 May;146(3):257-60. doi: 10.1007/BF00716469.
6
The isolation and properties of granulocytic colony-stimulating activities from medium conditioned by human peripheral leucocytes.人外周血白细胞条件培养液中粒细胞集落刺激活性的分离及特性
Biochem J. 1975 May;148(2):209-17. doi: 10.1042/bj1480209.
7
Release of colony-stimulating activity from thymus-derived lymphocytes.胸腺来源淋巴细胞释放集落刺激活性。
J Clin Invest. 1975 Mar;55(3):520-7. doi: 10.1172/JCI107958.
8
Factors influencning mitotic yields from suspension cultures of normal and acute leukaemic bone marrows.影响正常和急性白血病骨髓悬浮培养物有丝分裂产量的因素。
J Clin Pathol. 1976 Jul;29(7):583-6. doi: 10.1136/jcp.29.7.583.
9
[The agar culture of the leucopoietic stem cell (CFU-C) and its stimulation (author's transl)].[白细胞生成干细胞(CFU-C)的琼脂培养及其刺激作用(作者译)]
Klin Wochenschr. 1978 Oct 1;56(19):943-51. doi: 10.1007/BF01480148.
10
Corticosteroid effect on granulopoiesis in mice after cyclophosphamide.环磷酰胺处理后皮质类固醇对小鼠粒细胞生成的影响。
J Clin Invest. 1977 Aug;60(2):277-83. doi: 10.1172/JCI108775.