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1
Factors influencning mitotic yields from suspension cultures of normal and acute leukaemic bone marrows.影响正常和急性白血病骨髓悬浮培养物有丝分裂产量的因素。
J Clin Pathol. 1976 Jul;29(7):583-6. doi: 10.1136/jcp.29.7.583.
2
Human bone marrow cytogenetics: growth factors stimulate metaphases for specific lineages.人类骨髓细胞遗传学：生长因子刺激特定谱系的中期细胞。
Leukemia. 1989 Jun;3(6):405-12.
3
In vitro culture of leukaemic cells from 81 patients with acute leukaemia.对81例急性白血病患者的白血病细胞进行体外培养。
Scand J Haematol. 1977 May;18(5):377-94. doi: 10.1111/j.1600-0609.1977.tb02092.x.
4
In vitro colony growth of acute myelogenous leukemia.急性髓性白血病的体外集落生长
Nouv Rev Fr Hematol Blood Cells. 1976;17(1-2):125-37. doi: 10.1007/978-3-642-66312-3_8.
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Response of human myeloid leukemia cells to various sources of colony-stimulating activity and phytohemagglutinin-conditioned medium.人髓性白血病细胞对各种集落刺激活性来源及植物血凝素条件培养基的反应。
Cancer Res. 1983 May;43(5):2350-7.
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Leukemia-derived dendritic cells can be generated from blood or bone marrow cells from patients with acute myeloid leukaemia: a methodological approach under serum-free culture conditions.急性髓系白血病患者的血液或骨髓细胞可生成白血病来源的树突状细胞：无血清培养条件下的一种方法学途径。
Scand J Immunol. 2005 Jul;62(1):86-98. doi: 10.1111/j.1365-3083.2005.01630.x.
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Lancet. 1975 Oct 11;2(7937):696-9. doi: 10.1016/s0140-6736(75)90788-6.
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Polyploidy of the bone marrow.骨髓的多倍体现象。
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Cytogenetic study of maturing granulocytes in bone marrow of patients with acute myelogenous leukemia.急性髓性白血病患者骨髓中成熟粒细胞的细胞遗传学研究。
Leukemia. 1990 Apr;4(4):297-301.

本文引用的文献

1
Chromosome preparations of bone marrow cells without prior in vitro culture or in vivo colchicine administration.未经预先体外培养或体内给予秋水仙碱的骨髓细胞染色体标本制备。
Stain Technol. 1962 Jan;37:17-20. doi: 10.3109/10520296209114563.
2
Bone marrow colonies: stimulation in vitro by supernatant from incubated human blood cells.骨髓集落：人血细胞孵育上清液在体外的刺激作用
Science. 1970 Aug 14;169(3946):691-2. doi: 10.1126/science.169.3946.691.
3
Studies of cellular proliferation in human leukemia. I. Estimation of growth rates of leukemic and normal hematopoietic cells in two adults with acute leukemia given single injections of tritiated thymidine.人类白血病细胞增殖的研究。I. 对两名接受单次氚标记胸腺嘧啶核苷注射的急性白血病成年患者的白血病细胞和正常造血细胞生长速率的估计。
J Clin Invest. 1967 Apr;46(4):506-29. doi: 10.1172/JCI105553.
4
Regulation of granulocyte and monocyte-macrophage proliferation by colony stimulating factor (CSF): a review.集落刺激因子（CSF）对粒细胞和单核细胞-巨噬细胞增殖的调节：综述
Exp Hematol. 1973;1(4):185-201.
5
In vitro colony forming cells and colony stimulating factor in chronic granulocytic leukaemia.慢性粒细胞白血病中的体外集落形成细胞和集落刺激因子
Br J Cancer. 1974 Jul;30(1):1-12. doi: 10.1038/bjc.1974.108.
6
Studies of cellular proliferation in human leukemia. 3. Behavior of leukemic cells in three adults with acute leukemia given continuous infusions of 3H-thymidine for 8 or 10 days.人类白血病细胞增殖的研究。3. 三名成年急性白血病患者连续8天或10天输注³H-胸腺嘧啶核苷时白血病细胞的行为。
Cancer. 1970 Jun;25(6):1237-60. doi: 10.1002/1097-0142(197006)25:6<1237::aid-cncr2820250602>3.0.co;2-7.

影响正常和急性白血病骨髓悬浮培养物有丝分裂产量的因素。

Factors influencning mitotic yields from suspension cultures of normal and acute leukaemic bone marrows.

作者信息

Lawler S D, Summersgill B M, Lewis J P

出版信息

J Clin Pathol. 1976 Jul;29(7):583-6. doi: 10.1136/jcp.29.7.583.

DOI:10.1136/jcp.29.7.583
PMID:1086308
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC476121/
Abstract

Cytogenetic studies of bone marrow are often hampered by a paucity of dividing cells. In an attempt to improve mitotic yields we have tried to promote mitotic activity in suspension cultures of bone marrow from both normal and leukaemic subjects. Enrichment of the media always increases yield and the addition of bone marrow stimulating factor (BMSF) may do so. The best prospect for improving the yield of mitoses in acute myeloid leukaemia is to culture the marrow in an enriched medium with BMSF.

摘要

骨髓的细胞遗传学研究常常因分裂细胞数量稀少而受阻。为了提高有丝分裂产量，我们尝试在正常和白血病患者的骨髓悬浮培养物中促进有丝分裂活性。培养基的富集总能提高产量，添加骨髓刺激因子（BMSF）可能也有此效果。提高急性髓性白血病有丝分裂产量的最佳方法是在富含BMSF的培养基中培养骨髓。