Ganovski Kh, Shipochliev T, Bratova K
Vet Med Nauki. 1979;16(7):54-61.
It was established by a series of experiments with white Wistar rats that intraperitoneal injection of water extracts (infusions) of a mixed sample of dried algae (Cystosira barbata, Ulva lactica and Zostera nona) collected at the Bourgas coastal region, respectively leveled to an isotonic solution by use of 0.9% NaCl produces well expressed antiinflammatory effect in Caragina provoked oedema. The mixed sample of algae has LD0--0.250 g dry drug per kg body weight, LD'100--0.500 g/kg b. w. and LD50--0.407 g/kg b. w. The therapeutic index of the algae is relatively high -- LD50/U50+20.
通过对白色Wistar大鼠进行一系列实验确定,腹腔注射在布尔加斯沿海地区采集的干藻(硬囊藻、乳状石莼和波叶海泽藻)混合样本的水提取物(浸液),该提取物通过使用0.9%氯化钠分别调至等渗溶液后,对卡拉胶诱发的水肿产生了明显的抗炎作用。藻类混合样本的LD0为每千克体重0.250克干药,LD'100为0.500克/千克体重,LD50为0.407克/千克体重。藻类的治疗指数相对较高——LD50/U50+20。