脉孢菌中犬尿氨酸酶的诱导
Induction of kynureninase in Neurospora.
作者信息
Turner J R, Sorsoli W A, Matchett W H
出版信息
J Bacteriol. 1970 Aug;103(2):364-9. doi: 10.1128/jb.103.2.364-369.1970.
Abstract
Induction of kynureninase in a homogeneous population of mycelia in balanced growth was studied. Induced synthesis of enzyme was apparent 10 min after addition of inducers (tryptophan, kynurenine, and N-formylkynurenine). Experiments with cycloheximide-inhibited cells indicated that initiation of message transcription occurred about 4 min after addition of inducers. Lifetime of the message in the absence of inducer was of the order of 5 min. Experiments with mutants showed that N-formylkynurenine was the probable inducer of physiological importance.
摘要
研究了在平衡生长的菌丝体同质群体中犬尿氨酸酶的诱导情况。在添加诱导剂（色氨酸、犬尿氨酸和N-甲酰犬尿氨酸）10分钟后，酶的诱导合成明显可见。用环己酰亚胺抑制细胞的实验表明，在添加诱导剂约4分钟后开始进行信使转录。在没有诱导剂的情况下，信使的寿命约为5分钟。对突变体的实验表明，N-甲酰犬尿氨酸可能是具有生理重要性的诱导剂。
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引用本文的文献
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2
Cross-pathway regulation: histidine-mediated control of histidine, tryptophan, and arginine biosynthetic enzymes in Neurospora crassa.跨途径调控：粗糙脉孢菌中组氨酸介导的对组氨酸、色氨酸和精氨酸生物合成酶的控制
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Evidence for a Tryptophane Cycle in Neurospora.关于粗糙脉孢菌中色氨酸循环的证据。
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On the induced synthesis of an enzyme required for biosynthesis of an essential metabolite: induced kynureninase synthesis in Neurospora crassa.关于必需代谢物生物合成所需酶的诱导合成：粗糙脉孢菌中犬尿氨酸酶的诱导合成
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Comparative inductive responses of two beta-galactosidases of Neurospora.粗糙脉孢菌两种β-半乳糖苷酶的比较诱导反应
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Alteration of tryptophan-mediated regulation in Neurospora crassa by indoleglycerol phosphate.吲哚甘油磷酸对粗糙脉孢菌中色氨酸介导的调控的改变。
J Bacteriol. 1968 May;95(5):1608-14. doi: 10.1128/jb.95.5.1608-1614.1968.
10
Temporal separation of transcription and translation in Neurospora.脉孢菌中转录与翻译的时间分离。
J Bacteriol. 1970 Aug;103(2):370-4. doi: 10.1128/jb.103.2.370-374.1970.
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