Dyer J A
Ophthalmology. 1979 May;86(5):692-4. doi: 10.1016/s0161-6420(79)35459-8.
Atropine sulfate 1% was instilled in both eyes of 86 children (172 eyes) on a daily basis for a period of two to eight years. No untoward changes in intraocular pressure, pupillary response, accommodation, or appearance of the ocular fundi were noted. A comparison with a similar group of children having only glasses prescribed during a similar time span revealed that atropine is effective in reducing theprogression of myopia in children; a permanent reduction in the degree of myopia may be achieved. Relaxation of accommodation by means of cycloplegic drugs may be a safe and effective treatment of myopia.
对86名儿童(172只眼)每天双眼滴入1%硫酸阿托品,持续两至八年。未发现眼压、瞳孔反应、调节功能或眼底外观有不良变化。与在相似时间段仅配镜的一组相似儿童进行比较发现,阿托品可有效减缓儿童近视进展;可实现近视度数的永久性降低。通过睫状肌麻痹药物放松调节功能可能是一种安全有效的近视治疗方法。