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成人乳糜泻和疱疹样皮炎中膳食叶酸(蝶酰多聚谷氨酸)的吸收不良。

Malabsorption of dietary folate (Pteroylpolyglutamates) in adult coeliac disease and dermatitis herpetiformis.

作者信息

Hoffbrand A V, Douglas A P, Fry L, Stewart J S

出版信息

Br Med J. 1970 Oct 10;4(5727):85-9. doi: 10.1136/bmj.4.5727.85.

DOI:10.1136/bmj.4.5727.85
PMID:5471775
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1819649/
Abstract

Tests of absorption of folic acid (pteroylglutamic acid) and of dietary folates (pteroylpolyglutamates) were performed in 10 patients with untreated adult coeliac disease, five with dermatitis herpetiformis, and three with nutritional folate deficiency. Absorption of pteroylglutamic acid was impaired in eight patients with coeliac disease and in two with dermatitis herpetiformis. Absorption of pteroylpolyglutamates was impaired in all 10 coeliac patients and in four of the five patients with dermatitis herpetiformis. Absorption of both forms of folate was normal in all three patients with nutritional folate deficiency.

摘要

对10例未经治疗的成人乳糜泻患者、5例疱疹样皮炎患者和3例营养性叶酸缺乏患者进行了叶酸(蝶酰谷氨酸)和膳食叶酸(蝶酰多谷氨酸)吸收测试。8例乳糜泻患者和2例疱疹样皮炎患者的蝶酰谷氨酸吸收受损。10例乳糜泻患者和5例疱疹样皮炎患者中的4例的蝶酰多谷氨酸吸收受损。3例营养性叶酸缺乏患者的两种叶酸形式的吸收均正常。

相似文献

1
Malabsorption of dietary folate (Pteroylpolyglutamates) in adult coeliac disease and dermatitis herpetiformis.成人乳糜泻和疱疹样皮炎中膳食叶酸(蝶酰多聚谷氨酸)的吸收不良。
Br Med J. 1970 Oct 10;4(5727):85-9. doi: 10.1136/bmj.4.5727.85.
2
Amino acid and peptide absorption in patients with coeliac disease and dermatitis herpetiformis.乳糜泻和疱疹样皮炎患者的氨基酸和肽吸收情况
Gut. 1974 Jan;15(1):1-8. doi: 10.1136/gut.15.1.1.
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Jejunal function in dermatitis herpetiformis and adult coeliac disease.
Gut. 1972 Apr;13(4):322.
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Intestinal permeability in patients with coeliac disease and dermatitis herpetiformis.乳糜泻和疱疹样皮炎患者的肠道通透性
Gut. 1985 Nov;26(11):1214-9. doi: 10.1136/gut.26.11.1214.
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Conventional malabsorption tests: do they detect the adult patient with villous atrophy?
Scand J Clin Lab Invest. 1984 Feb;44(1):91-8. doi: 10.3109/00365518409083792.
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The absorption of dapsone by patients with dermatitis herpetiformis and coeliac disease.疱疹样皮炎和乳糜泻患者对氨苯砜的吸收情况。
Clin Exp Dermatol. 1980 Mar;5(1):27-30. doi: 10.1111/j.1365-2230.1980.tb01660.x.
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Assessment of jejunal function in patients with dermatitis herpetiformis and adult coeliac disease using a perfusion technique.采用灌注技术评估疱疹样皮炎和成人乳糜泻患者的空肠功能。
Scand J Gastroenterol. 1974 Nov;9(8):793-8.
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Folic acid malabsorption in cardiac failure.心力衰竭中的叶酸吸收不良。
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Availability of monoglutamyl and polyglutamyl folates in normal subjects and in patients with coeliac sprue.正常受试者和乳糜泻患者体内单谷氨酰叶酸和多谷氨酰叶酸的可用性。
Gut. 1978 Oct;19(10):886-91. doi: 10.1136/gut.19.10.886.
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Dermatitis herpetiformis--a disease associated with intestinal malabsorption.疱疹样皮炎——一种与肠道吸收不良相关的疾病。
Am J Gastroenterol. 1971 Jan;55(1):21-32.

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Availability of monoglutamyl and polyglutamyl folates in normal subjects and in patients with coeliac sprue.正常受试者和乳糜泻患者体内单谷氨酰叶酸和多谷氨酰叶酸的可用性。
Gut. 1978 Oct;19(10):886-91. doi: 10.1136/gut.19.10.886.
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Gluten challenge in treated coeliac disease.经治疗的乳糜泻患者的麸质激发试验
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本文引用的文献

1
INTESTINAL ABSORPTION OF TRITUM-LABELLED FOLIC ACID IN IDIOPATHIC STEATORRHEA: EFFECT OF A GLUTENFREE DIET.特发性脂肪泻中氚标记叶酸的肠道吸收:无麸质饮食的影响
Can Med Assoc J. 1963 Nov 9;89(19):975-9.
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Studies on the folic acid activity of human serum.人体血清叶酸活性的研究。
J Clin Pathol. 1961 Jul;14(4):335-44. doi: 10.1136/jcp.14.4.335.
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The urinary and faecal excretion of radioactivity after oral doses of H3-folic acid.口服H3-叶酸后放射性物质的尿排泄和粪排泄。
Br J Haematol. 1960 Oct;6:439-55. doi: 10.1111/j.1365-2141.1960.tb06262.x.
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The absorption of folic acid.叶酸的吸收
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Intraluminal biopsy of the small intestine; the intestinal biopsy capsule.小肠腔内活检;肠道活检胶囊
Am J Dig Dis. 1957 May;2(5):236-41. doi: 10.1007/BF02231100.
6
A folic-acid excretion test in the investigation of intestinal malabsorption.用于肠道吸收不良研究的叶酸排泄试验。
Lancet. 1953 Jul 11;265(6776):53-60. doi: 10.1016/s0140-6736(53)91084-8.
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A study of proximal and distal intestinal structure and absorptive function in idiopathic steatorrhoea.特发性脂肪泻患者近端及远端肠道结构与吸收功能的研究
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8
Water and solute movement in the small intestine of patients with sprue.口炎性腹泻患者小肠内水和溶质的移动
J Clin Invest. 1967 Mar;46(3):287-98. doi: 10.1172/JCI105531.
9
A histochemical study on the role of lysosomal enzymes in idiopathic steatorrhoea before and during a gluten-free diet.关于无麸质饮食前后溶酶体酶在特发性脂肪泻中作用的组织化学研究
Gut. 1966 Aug;7(4):317-32. doi: 10.1136/gut.7.4.317.
10
Malabsorption of folate polyglutamates in tropical sprue.热带口炎性腹泻中叶酸多聚谷氨酸的吸收不良
Br Med J. 1969 May 31;2(5656):543-7. doi: 10.1136/bmj.2.5656.543.