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1
Lipid metabolism in the perfused chicken liver. Lipogenesis from glucose, acetate and palmitate.灌注鸡肝中的脂质代谢。葡萄糖、乙酸盐和棕榈酸盐的脂肪生成。
Biochem J. 1970 Jul;118(3):427-31. doi: 10.1042/bj1180427.
2
The immediate effects of insulin and fructose on the metabolism of the perfused liver. Changes in lipoprotein secretion, fatty acid oxidation and esterification, lipogenesis and carbohydrate metabolism.胰岛素和果糖对灌注肝脏代谢的即时影响。脂蛋白分泌、脂肪酸氧化与酯化、脂肪生成及碳水化合物代谢的变化。
Biochem J. 1972 Jan;126(2):295-311. doi: 10.1042/bj1260295.
3
Effects of dichloroacetate on the metabolism of glucose, pyruvate, acetate, 3-hydroxybutyrate and palmitate in rat diaphragm and heart muscle in vitro and on extraction of glucose, lactate, pyruvate and free fatty acids by dog heart in vivo.二氯乙酸对大鼠膈肌和心肌体外葡萄糖、丙酮酸、乙酸、3-羟基丁酸和棕榈酸代谢以及对犬心脏体内葡萄糖、乳酸、丙酮酸和游离脂肪酸摄取的影响。
Biochem J. 1973 Aug;134(4):1067-81. doi: 10.1042/bj1341067.
4
Studies of the metabolism of isolated livers of normal and alloxan-diabetic rats perfused with insulin.对用胰岛素灌注的正常大鼠和四氧嘧啶糖尿病大鼠的离体肝脏代谢的研究。
Diabetes. 1968 May;17(5):244-50. doi: 10.2337/diab.17.5.244.
5
Interrelationships and metabolic effects of fatty acids in the perfused rat liver at hyperthermic temperatures.高温下灌注大鼠肝脏中脂肪酸的相互关系及代谢效应。
Cancer Biochem Biophys. 1985 Jun;8(1):9-22.
6
Lipid metabolism of rat liver isolated and perfused in hypoxia.缺氧条件下分离并灌注的大鼠肝脏的脂质代谢
Biomedicine. 1974 Mar;20(2):154-9.
7
Metabolism of a tracer dose of palmitate-1-C14 by liver of normal and diabetic rats perfused with and without the addition of insulin.用添加和不添加胰岛素灌注的正常大鼠和糖尿病大鼠肝脏对微量棕榈酸 -1-C14 的代谢。
Metabolism. 1968 Sep;17(9):818-24. doi: 10.1016/0026-0495(68)90033-4.
8
Effect of dietary protein on hepatic lipogenesis in the growing chick.日粮蛋白质对生长鸡肝脏脂肪生成的影响。
J Nutr. 1969 Jul;98(3):356-66. doi: 10.1093/jn/98.3.356.
9
Effects of insulin on metabolism of perfused livers of rats made acutely diabetic by anti-insulin serum injection.胰岛素对通过注射抗胰岛素血清使大鼠急性糖尿病化后的灌注肝脏代谢的影响。
Diabetes. 1968 May;17(5):251-5. doi: 10.2337/diab.17.5.251.
10
The source of cellular lipid in the human diploid cell strain WI-38.人二倍体细胞株WI-38中细胞脂质的来源。
Biochim Biophys Acta. 1969 Oct 28;187(3):293-301. doi: 10.1016/0005-2760(69)90002-2.

引用本文的文献

1
Dietary Flavonoids as Modulators of Lipid Metabolism in Poultry.膳食类黄酮作为家禽脂质代谢的调节剂。
Front Physiol. 2022 Apr 25;13:863860. doi: 10.3389/fphys.2022.863860. eCollection 2022.
2
Lipid metabolism in the perfused chicken liver. The uptake and metabolism of oleic acid, elaidic acid, cis-vaccenic acid, trans-vaccenic acid and stearic acid.灌注鸡肝中的脂质代谢。油酸、反油酸、顺式-11-十八碳烯酸、反式-11-十八碳烯酸和硬脂酸的摄取与代谢。
Biochem J. 1970 Jul;118(3):433-42. doi: 10.1042/bj1180433.
3
Urate synthesis in the perfused chicken liver.灌注鸡肝中的尿酸合成。
Biochem J. 1972 Sep;129(2):20P. doi: 10.1042/bj1290020pa.
4
Urate synthesis in the perfused chick liver.灌注鸡肝中的尿酸合成。
Biochem J. 1974 Nov;144(2):189-98. doi: 10.1042/bj1440189.
5
Developmental changes in hepatic fructose 2,6-bisphosphate content and phosphofructokinase-1 activity in the transition of chicks from embryonic to neonatal nutritional environment.雏鸡从胚胎营养环境过渡到新生营养环境过程中肝脏果糖-2,6-二磷酸含量和磷酸果糖激酶-1活性的发育变化。
Biochem J. 1987 Jul 1;245(1):35-9. doi: 10.1042/bj2450035.
6
The use of viable hepatocytes to study the hormonal control of glycogenolysis in the chicken.利用活肝细胞研究鸡糖原分解的激素调控。
Mol Cell Biochem. 1978 Apr 11;19(2):81-92. doi: 10.1007/BF00232598.

本文引用的文献

1
DETERMINATION OF THE SPECIFIC ACTIVITY OF LABELED BLOOD GLUCOSE BY LIQUID SCINTILLATION USING GLUCOSE PENTAACETATE.使用葡萄糖五乙酸酯通过液体闪烁法测定标记血糖的比活性。
Anal Biochem. 1965 Aug;12:249-58. doi: 10.1016/0003-2697(65)90088-6.
2
PATHWAY AND FORM OF ABSORPTION OF PALMITIC ACID IN THE CHICKEN.鸡体内棕榈酸的吸收途径与形式
J Lipid Res. 1964 Oct;5:538-41.
3
METABOLIC INTERRELATIONS OF GLUCOSE AND LACTATE IN SHEEP.绵羊体内葡萄糖与乳酸的代谢相互关系
Biochem J. 1963 Aug;88(2):243-8. doi: 10.1042/bj0880243.
4
Use of glucose oxidase, peroxidase, and O-dianisidine in determination of blood and urinary glucose.葡萄糖氧化酶、过氧化物酶和邻联茴香胺在血液及尿液葡萄糖测定中的应用
Lancet. 1957 Aug 24;273(6991):368-70. doi: 10.1016/s0140-6736(57)92595-3.
5
Serum glutamic pyruvic transaminase in cardiac with hepatic disease.心脏合并肝脏疾病时的血清谷丙转氨酶
Proc Soc Exp Biol Med. 1956 Apr;91(4):569-71. doi: 10.3181/00379727-91-22330.
6
Gluconeogenesis in the perfused rat liver.灌注大鼠肝脏中的糖异生作用。
Biochem J. 1966 Nov;101(2):284-92. doi: 10.1042/bj1010284.
7
In vivo lipogenesis in the domestic chicken.家鸡体内的脂肪生成
Proc Soc Exp Biol Med. 1968 Jun;128(2):398-401. doi: 10.3181/00379727-128-33022.
8
Lipid metabolism in the perfused chicken liver. The uptake and metabolism of oleic acid, elaidic acid, cis-vaccenic acid, trans-vaccenic acid and stearic acid.灌注鸡肝中的脂质代谢。油酸、反油酸、顺式-11-十八碳烯酸、反式-11-十八碳烯酸和硬脂酸的摄取与代谢。
Biochem J. 1970 Jul;118(3):433-42. doi: 10.1042/bj1180433.

灌注鸡肝中的脂质代谢。葡萄糖、乙酸盐和棕榈酸盐的脂肪生成。

Lipid metabolism in the perfused chicken liver. Lipogenesis from glucose, acetate and palmitate.

作者信息

Bickerstaffe R, West C E, Annison E F

出版信息

Biochem J. 1970 Jul;118(3):427-31. doi: 10.1042/bj1180427.

DOI:10.1042/bj1180427
PMID:5472168
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1179209/
Abstract

A procedure for the perfusion of the isolated chicken liver was developed. The preparation satisfied many of the criteria of normal physiological function, e.g. oxygen consumption and the absence in the perfusion medium of enzymes indicative of cell damage, and retained its capacity to synthesize lipids from glucose, acetate and long-chain fatty acids. Part of newly synthesized triglyceride was released into the perfusion medium as lipoprotein.

摘要

开发了一种用于灌注离体鸡肝的方法。该制剂满足许多正常生理功能的标准,例如耗氧量以及灌注介质中不存在指示细胞损伤的酶,并且保留了从葡萄糖、乙酸盐和长链脂肪酸合成脂质的能力。新合成的甘油三酯的一部分作为脂蛋白释放到灌注介质中。