Murphy D B, Shreffler D C
Transplantation. 1975 Dec;20(6):443-56. doi: 10.1097/00007890-197512000-00002.
Absorption analyses were conducted on antisera which had previously been shown to detect cross reactivity between the H-2K and H-2D gene products. These analyses revealed that the cross reactions were due to known public H-2 specificities. Identification of cross reactive anti-H-2.3 and anti H-2.5 antibodies confirmed earlier predictions that genes controlling these specificities should be localized at opposite ends of the H-2 complex. The finding of H-2.29 activity on both sides of the S region clarified ambiguities encountered in assigning this specificity to certain recombinant types. Results with H-2.36 support the suggestion that this determinant may also be specified by both H-2K and H-2D genes.
对先前已证明能检测H-2K和H-2D基因产物之间交叉反应性的抗血清进行了吸收分析。这些分析表明，交叉反应是由于已知的公共H-2特异性。交叉反应性抗H-2.3和抗H-2.5抗体的鉴定证实了早期的预测，即控制这些特异性的基因应定位在H-2复合体的相对两端。在S区域两侧发现H-2.29活性，澄清了在将这种特异性指定给某些重组类型时遇到的模糊性。H-2.36的结果支持了这一观点，即这种决定簇也可能由H-2K和H-2D基因共同指定。
