Walker B E, Bone I, Mascie-Taylor B H, Kelleher J
Int J Vitam Nutr Res. 1979;49(4):413-8.
Plasma zinc is totally protein bound and its concentration is markedly influenced by alteration in protein concentration. Venous occlusion such as is used prior to venepuncture causes a marked increase in plasma zinc concentration. The extent of this change exceeds the analytical variation for zinc determination and may cause difficulty in the interpretation of plasma values. Although in most individuals there is a close correlation between plasma zinc and total protein, collectively this is not so, thus adjusting zinc values for change in protein is inappropriate. For plasma zinc to be a useful investigation blood samples should be obtained without venous occlusion.
血浆锌完全与蛋白质结合，其浓度受蛋白质浓度变化的显著影响。静脉穿刺前使用的静脉闭塞会导致血浆锌浓度显著升高。这种变化的程度超过了锌测定的分析变异，可能会导致血浆值解释困难。尽管在大多数个体中血浆锌与总蛋白密切相关，但总体并非如此，因此针对蛋白质变化调整锌值是不合适的。为了使血浆锌成为一项有用的检查，应在不进行静脉闭塞的情况下采集血样。
