地中海贫血患儿的生长：不同输血方案的影响。
Growth of children with thalassaemia: effect of different transfusion regimens.
作者信息
Kattamis C, Touliatos N, Haidas S, Matsaniotis N
出版信息
Arch Dis Child. 1970 Aug;45(242):502-9. doi: 10.1136/adc.45.242.502.
Abstract
Growth was studied in 74 children with homozygous β-thalassaemia aged 1 to 11 years, treated with three different transfusion regimens. In group I (38 cases) haemoglobin levels were maintained above 8 g./100 ml.; in group II (14 cases), pretransfusion haemoglobin levels ranged between 6 and 8 g./100 ml.; in group III (22 children), pretransfusion haemoglobin levels were below 6 g./100 ml. Children in group I grew normally, both in weight and height; those in groups II and III were retarded, particularly those in group III. Frequent transfusions, in spite of their disadvantages, at present constitute the treatment of choice.
摘要
对74名1至11岁的纯合子β地中海贫血患儿进行了生长情况研究，这些患儿接受了三种不同的输血方案治疗。第一组（38例）血红蛋白水平维持在8g/100ml以上；第二组（14例）输血前血红蛋白水平在6至8g/100ml之间；第三组（22名儿童）输血前血红蛋白水平低于6g/100ml。第一组儿童的体重和身高均正常增长；第二组和第三组儿童发育迟缓，尤其是第三组。尽管频繁输血存在缺点，但目前仍是首选治疗方法。
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