Cristol R, Graisely B, Cloarec M, Debray J
Nouv Presse Med. 1979 Jan 13;8(2):105-8.
The fingertip blood flow was measured by venous occlusion plethysmography in a room at 22 degrees C, in 52 patients with Raynaud's syndrome and 24 healthy controls. In severe Raynaud's syndroms (24 cases incuding: scleroderma: 7 cases, thromboangitis: 5 cases, disabling syndrom without known etiology: 12 cases), the flow was significantly lower than in moderate Raynaud's syndroms (19 cases including 10 primary and 9 secondary syndroms) i.d. 7.5 +/- 7.3 ml versus 25 +/- 15 ml (p < 0.001). Controls had significantly higher flow (35 +/- 12.3 ml) than moderate Raynaud's syndroms (p < 0.05). Raynaud's syndroms with permanent acrocyanosis had a low flow (8.7 +/- 5.3 ml) not different from severe syndroms.
在22摄氏度的房间里,采用静脉阻塞体积描记法对52例雷诺综合征患者和24名健康对照者的指尖血流进行了测量。在严重雷诺综合征(24例,包括:硬皮病7例、血栓闭塞性脉管炎5例、病因不明的致残综合征12例)中,血流显著低于中度雷诺综合征(19例,包括10例原发性和9例继发性综合征),即分别为7.5±7.3毫升和25±15毫升(p<0.001)。对照组的血流(35±12.3毫升)显著高于中度雷诺综合征(p<0.05)。伴有永久性手足发绀的雷诺综合征血流较低(8.7±5.3毫升),与严重综合征无差异。