Wouda A A
Acta Med Scand. 1977;201(6):519-23.
A study has been made of the changes in the amplitudes shown on photoelectric plethysmographs of the fingers of one hand of controls (17 men and 17 women without Raynaud's phenomenon) during cooling and warming up of the hand. This is called the cooling and warming up test. The hands of the women appeared to cool more quickly than of the men, besides getting warm more quickly and remaining warm for a longer period. This difference is already apparent at the lowest water temperatures (6 and 3 degrees C) and may be ascribed to a difference in hand volume, with a hunting reaction due to extreme cold. The lowest values of controls appear to be useful for the clinical differentiation of patients with a serious Raynaud's phenomenon. The test is said to be positive when the values are below the lowest values of the controls. The test was performed on 50 of 58 out-patients suffering from Raynaud's phenomenon. In serious cases the severity of the disease could be assessed objectively. In less serious cases the test was sometimes negative.
对一组对照人群（17名男性和17名无雷诺现象的女性）一只手的手指进行光电体积描记，研究手部冷却和复温过程中所显示的振幅变化。这被称为冷却和复温试验。结果发现，女性的手似乎比男性冷却得更快，此外升温也更快，且保持温暖的时间更长。这种差异在最低水温（6摄氏度和3摄氏度）时就已明显，可能归因于手部体积的差异，以及极寒导致的异常反应。对照人群的最低值似乎有助于对患有严重雷诺现象的患者进行临床鉴别。当数值低于对照人群的最低值时，该试验被认为呈阳性。对58名患有雷诺现象的门诊患者中的50名进行了该试验。在严重病例中，可以客观评估疾病的严重程度。在不太严重的病例中，该试验有时呈阴性。
