影响酿酒酵母中几种不同氨基酸转运系统活性的突变。
Mutation affecting activity of several distinct amino acid transport systems in Saccharomyces cerevisiae.
作者信息
Grenson M, Hennaut C
出版信息
J Bacteriol. 1971 Feb;105(2):477-82. doi: 10.1128/jb.105.2.477-482.1971.
Abstract
Mutations at the apf locus selectively depress the activity of a number of distinct amino acid permeases in Saccharomyces cerevisiae. The activity of the general amino acid permease and specific amino acid permeases is decreased, but the uptake of pyrimidines and adenine is unaffected. Mutations at the apf locus are allelic to the aap mutation isolated by Surdin et al. Amino acid uptake is normal in a heterozygous diploid (apf/+) and in a tetraploid strain with only one functional allele at the apf locus.
摘要
apf基因座处的突变选择性地降低了酿酒酵母中多种不同氨基酸通透酶的活性。一般氨基酸通透酶和特定氨基酸通透酶的活性降低，但嘧啶和腺嘌呤的摄取不受影响。apf基因座处的突变与Surdin等人分离出的aap突变等位。在杂合二倍体（apf/+）和apf基因座只有一个功能等位基因的四倍体菌株中，氨基酸摄取正常。
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