Spicer A J
Trans R Soc Trop Med Hyg. 1979;73(4):415-7. doi: 10.1016/0035-9203(79)90166-4.
The possible role of Coxiella burneti as a cause of chronic liver disease in man was investigated in Cyprus. Serology, using the complement fixation test and phase 1 and phase 2 antigens, was performed on 16 patients with cryptogenic cirrhosis and two patients with chronic active hepatitis. Antibody studies were also done on 106 adult Cypriot villagers and on 13 shepherds from flocks infected with C. burneti, to provide a base line for comparative purposes. No evidence was found to implicate the organism as a cause of chronic liver disease. As the number of patients investigated was small it was not possible to exclude C. burneti as an occasional pathogen, and guiding principles were formulated for future investigations.
在塞浦路斯，对伯氏考克斯氏体作为人类慢性肝病病因的可能作用进行了调查。使用补体结合试验以及1期和2期抗原，对16例隐源性肝硬化患者和2例慢性活动性肝炎患者进行了血清学检测。还对106名成年塞浦路斯村民和13名来自感染伯氏考克斯氏体羊群的牧羊人进行了抗体研究，以提供比较的基线。未发现该病原体与慢性肝病病因有关的证据。由于所调查的患者数量较少，无法排除伯氏考克斯氏体作为偶发病原体的可能性，并制定了未来调查的指导原则。
