Dzierzawski A
Pol Arch Weter. 1979;22(2):263-87.
Embryotoxic and teratogenic effects of phenyl mercury acetate and methyl mercury chloride were studied on 66 pregnant females of golden hamster, 86 rats, and 62 rabbits. The mercury compounds were given by the stomach tube from the 5th to 12th days of pregnancy once or three times in single doses ranged from 1-6 to 1-2 DL50. The obtained results indicated to the embryotoxic effects of phenyl mercury acetate. This compound induced resorptions, dead foetuses, retardation of the development, diminished cranial ossification, edemata of the body, haematomas and open eyes. The methyl mercury chloride proved to be embryotoxic and teratogenic. The compound produced similar embryotoxic lesions as did phenyl mercury acetate and induced developmental malformations of the foetus (e.g.: encephalocele and hernia spinalis).
研究了醋酸苯汞和氯化甲基汞对66只怀孕金黄地鼠、86只大鼠和62只家兔的胚胎毒性和致畸作用。在怀孕第5至12天，通过胃管给这些汞化合物，单次剂量为1 - 6至1 - 2 DL50，给药一次或三次。所得结果表明醋酸苯汞具有胚胎毒性作用。该化合物可引起吸收、死胎、发育迟缓、颅骨骨化减少、身体水肿、血肿和睁眼。氯化甲基汞被证明具有胚胎毒性和致畸性。该化合物产生了与醋酸苯汞类似的胚胎毒性损伤，并导致胎儿发育畸形（如：脑膨出和脊柱裂）。
