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一项关于麦麸对肠易激综合征症状影响的双盲试验。

A double-blind trial of the effect of wheat bran on symptoms of irritable bowel syndrome.

作者信息

Soltoft J, Krag B, Gudmand-Hoyer E, Kristensen E, Wulff H R

出版信息

Lancet. 1976 Feb 7;1(7954):270-2. doi: 10.1016/s0140-6736(76)91402-1.

DOI:10.1016/s0140-6736(76)91402-1
PMID:55586
Abstract

59 outpatients with irritable bowel syndrome participated in a randomised double-blind trial. The patients in the treatment group received three biscuits daily each containing 10 g of ordinary miller's bran, whereas the patients in the control group received wheat biscuits of a similar appearance. The treatment period was 6 weeks. 52% of the patients in the treatment group noted subjective improvement compared with 65% in the control group. The results of this trial do not support the routine use of miller's bran in irritable bowel syndrome.

摘要

59名肠易激综合征门诊患者参与了一项随机双盲试验。治疗组患者每天服用3块饼干,每块饼干含10克普通麦麸,而对照组患者服用外观相似的小麦饼干。治疗期为6周。治疗组52%的患者表示主观症状有所改善,而对照组这一比例为65%。该试验结果不支持在肠易激综合征中常规使用麦麸。

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A double-blind trial of the effect of wheat bran on symptoms of irritable bowel syndrome.一项关于麦麸对肠易激综合征症状影响的双盲试验。
Lancet. 1976 Feb 7;1(7954):270-2. doi: 10.1016/s0140-6736(76)91402-1.
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[Bran in the treatment of irritable colon. A double-blind controlled investigation].[麸 bran 治疗结肠过敏症。双盲对照研究]
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The Irritable Colon: The Family Physician's Most Common Gastroenterological Dilemma.肠易激综合征:家庭医生最常见的胃肠病难题。
Can Fam Physician. 1988 Mar;34:633-6.
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Management of irritable bowel syndrome in primary care: feasibility randomised controlled trial of mebeverine, methylcellulose, placebo and a patient self-management cognitive behavioural therapy website. (MIBS trial).基层医疗中肠易激综合征的管理:双八面体蒙脱石、甲基纤维素、安慰剂和患者自我管理认知行为疗法网站的可行性随机对照试验(MIBS 试验)。
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