特定抗原和化合物48-80促使牛肺释放多巴胺。
Release of dopamine from bovine lung by specific antigen and by compound 48-80.
作者信息
Eyre P
出版信息
Br J Pharmacol. 1971 Jul;42(3):423-7. doi: 10.1111/j.1476-5381.1971.tb07127.x.
Abstract
- Dopamine was shown to be released from the isolated lung of calves sensitized with horse serum by compound 48/80 and by specific antigen.2. Dopamine contracts the bovine pulmonary artery and pulmonary vein. Phentolamine, the alpha-adrenoceptor blocking agent, inhibits this activity of dopamine and also strongly reduces the Schultz-Dale response of the pulmonary vessels.3. The results are consistent with the suggestion that dopamine (together with histamine and 5-hydroxytryptamine) may participate in the pulmonary vasoconstriction associated with anaphylaxis in cattle.
摘要
已表明，在用48/80化合物和特异性抗原致敏的小牛离体肺中，多巴胺会被释放出来。
多巴胺可使牛肺动脉和肺静脉收缩。α-肾上腺素能受体阻断剂酚妥拉明可抑制多巴胺的这种活性，也能显著降低肺血管的舒尔茨-戴尔反应。
这些结果与以下观点一致，即多巴胺（与组胺和5-羟色胺一起）可能参与牛过敏反应相关的肺血管收缩。
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DOPAMINE AND MAST CELLS IN RUMINANTS.反刍动物中的多巴胺与肥大细胞
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Chromaffin cells, mast cells and melanin. II. The chromaffin cells of the liver capsule and gut in ungulates.嗜铬细胞、肥大细胞与黑色素。II. 有蹄类动物肝被膜和肠道的嗜铬细胞。
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A fluorimetric method for the determination of dopamine (3-hydroxytyramine).一种测定多巴胺（3-羟基酪胺）的荧光分析法。
Acta Physiol Scand. 1958 Dec 15;44(3-4):293-8. doi: 10.1111/j.1748-1716.1958.tb01628.x.
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Dopamine in mammalian lung and spleen.哺乳动物肺和脾中的多巴胺。
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Experimental anaphylaxis in cattle.牛的实验性过敏反应
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The Schultz-Dale reaction in bovine pulmonary smooth muscles.牛肺平滑肌中的舒尔茨-戴尔反应。
Br J Pharmacol. 1970 Sep;40(1):166P-167P.
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