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牛过敏性休克中激肽的产生。

Production of kinins in bovine anaphylactic shock.

作者信息

Eyre P, Lewis A J

出版信息

Br J Pharmacol. 1972 Feb;44(2):311-3. doi: 10.1111/j.1476-5381.1972.tb07269.x.

Abstract

Calves were sensitized by subcutaneous injection of horse serum in Freund's adjuvant. Subsequent challenge with intravenous horse serum induced increased blood kinin activity. This kinin activation correlated with the protracted fall in systemic blood pressure seen in the same animals.

摘要

通过在弗氏佐剂中皮下注射马血清使小牛致敏。随后静脉注射马血清进行激发,导致血液激肽活性增加。这种激肽激活与在相同动物中观察到的全身血压持续下降相关。

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