Pines A
Lancet. 1976 Feb 21;1(7956):380-1. doi: 10.1016/s0140-6736(76)90213-0.
Forty-eight patients with advanced squamous-cell lung cancer were treated with radical radiotherapy. Thereafter twenty-five received B.C.G. regularly and twenty-three did not. Differences in survival during the first year of observation and absence of peripheral metastases were significantly in favour of the patients treated with B.C.G. There was no response to B.C.G. in patients receiving palliative radiotherapy or cyclophosphamide nor in those with undifferentiated carcinoma.
48例晚期肺鳞状细胞癌患者接受了根治性放疗。此后,25例患者定期接受卡介苗治疗,23例未接受。在观察的第一年,接受卡介苗治疗的患者在生存率和无外周转移方面有显著优势。接受姑息性放疗或环磷酰胺治疗的患者以及未分化癌患者对卡介苗无反应。