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人类白细胞抗原(HLA)抗原与葡萄膜炎

HLA antigens and uveitis.

作者信息

Ohno S, Kimura S J, O'Connor G R, Char D H

出版信息

Br J Ophthalmol. 1977 Jan;61(1):62-4. doi: 10.1136/bjo.61.1.62.

Abstract

We have studied the antigen frequencies in a group of adult patients with acute and chronic iridocyclitis and chronic, cyclitis. In patients with iridocyclitis a statistically significant increased incidence of HLA-B27 was noted, even in those patients without joint or systemic disease. Patients with chronic iridocyclitis also were noted to have an increased incidence of B27; however, those patients with chronic cyclitis did not. On the basis of HLA-B27 studies there appears to be a fundamental difference between adult and juvenile iridocyclitis.

摘要

我们研究了一组患有急性和慢性虹膜睫状体炎以及慢性睫状体炎的成年患者的抗原频率。在虹膜睫状体炎患者中,即使是那些没有关节或全身性疾病的患者,也发现HLA - B27的发病率有统计学意义的增加。慢性虹膜睫状体炎患者也被发现B27的发病率增加;然而,慢性睫状体炎患者则没有。基于HLA - B27研究,成人和青少年虹膜睫状体炎之间似乎存在根本差异。

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