Shaw D M, MacSweeney D A, Woolcock N, Bevan-Jones A B
J Neurol Neurosurg Psychiatry. 1971 Jun;34(3):224-5. doi: 10.1136/jnnp.34.3.224.
In the search for paradigms of postulated abnormalities in indolamine function in the brain in affective disorders, 5-HT uptake and release was estimated in platelets from patients suffering from severe depressive illness. Neither of these measures was altered by the illness and the most likely explanation for the negative findings was that in this setting platelets are not a suitable model.
在寻找情感障碍中大脑吲哚胺功能假定异常的范例时,对重度抑郁症患者血小板中的5-羟色胺摄取和释放进行了评估。这两项测量结果均未因疾病而改变,对于这些阴性结果最可能的解释是,在这种情况下血小板并非合适的模型。