情感性疾病中血小板对14C-5-羟色胺的摄取与释放
Uptake and release of 14 C-5-hydroxytryptamine by platelets in affective illness.
作者信息
Shaw D M, MacSweeney D A, Woolcock N, Bevan-Jones A B
出版信息
J Neurol Neurosurg Psychiatry. 1971 Jun;34(3):224-5. doi: 10.1136/jnnp.34.3.224.
Abstract
In the search for paradigms of postulated abnormalities in indolamine function in the brain in affective disorders, 5-HT uptake and release was estimated in platelets from patients suffering from severe depressive illness. Neither of these measures was altered by the illness and the most likely explanation for the negative findings was that in this setting platelets are not a suitable model.
摘要
在寻找情感障碍中大脑吲哚胺功能假定异常的范例时，对重度抑郁症患者血小板中的5-羟色胺摄取和释放进行了评估。这两项测量结果均未因疾病而改变，对于这些阴性结果最可能的解释是，在这种情况下血小板并非合适的模型。
相似文献
1
Uptake and release of 14 C-5-hydroxytryptamine by platelets in affective illness.情感性疾病中血小板对14C-5-羟色胺的摄取与释放
J Neurol Neurosurg Psychiatry. 1971 Jun;34(3):224-5. doi: 10.1136/jnnp.34.3.224.
2
Lithium restores abnormal platelet 5-HT transport in patients with affective disorders.
Br J Psychiatry. 1980 Mar;136:235-8. doi: 10.1192/bjp.136.3.235.
3
Platelet 5-hydroxytryptamine accumulation in depressive illness.抑郁症中血小板5-羟色胺的积聚
Clin Chim Acta. 1978 Jul 1;87(1):165-8. doi: 10.1016/0009-8981(78)90071-2.
4
Effects of ergotamine and dihydroergotamine on uptake of 5-hydroxytryptamine in blood platelets.麦角胺和双氢麦角胺对血小板中5-羟色胺摄取的影响。
Eur J Pharmacol. 1970;13(1):76-82. doi: 10.1016/0014-2999(70)90185-8.
5
6
Tryptolines. Formation from tryptamines and 5-MTHF by human platelets.色满卡林。由人体血小板中的色胺和5-甲基四氢叶酸形成。
Arch Gen Psychiatry. 1974 Dec;31(6):862-7. doi: 10.1001/archpsyc.1974.01760180100013.
7
Effect of some anorectic agents on the uptake and release of 5-hydroxytryptamine by blood platelets of rats.
J Pharm Pharmacol. 1975 May;27(5):366-8. doi: 10.1111/j.2042-7158.1975.tb09458.x.
8
Differential uptake of biogenic amines by isolated 5-hydroxytryptamine organelles of blood platelets.血小板中分离出的5-羟色胺细胞器对生物胺的差异性摄取。
Life Sci. 1969 Jan 1;8(1):65-72. doi: 10.1016/0024-3205(69)90294-x.
9
Inhibitory effect of two newer antidepressants, Lu 5-003 and Lu 3-010, on serotonin uptake in human blood platelets in vitro.两种新型抗抑郁药Lu 5 - 003和Lu 3 - 010对人血小板5-羟色胺摄取的体外抑制作用
Psychopharmacologia. 1970;17(1):94-9. doi: 10.1007/BF00402095.
10
3-(4-Piperidinylalkyl)indoles, selective inhibitors of neuronal 5-hydroxytryptamine uptake.3-（4-哌啶基烷基）吲哚，神经元5-羟色胺摄取的选择性抑制剂。
J Med Chem. 1980 Dec;23(12):1306-10. doi: 10.1021/jm00186a005.
引用本文的文献
1
Serotonin transporter genotype and function in relation to antidepressant response in Koreans.与韩国人抗抑郁反应相关的 5-羟色胺转运体基因型和功能。
Psychopharmacology (Berl). 2013 Jan;225(2):283-90. doi: 10.1007/s00213-012-2813-y. Epub 2012 Aug 12.
2
Ect and platelet 5ht uptake in major depression.重性抑郁障碍患者的内皮素和血小板 5-羟色胺摄取。
Indian J Psychiatry. 1997 Oct;39(4):272-7.
3
Active platelet 5-ht uptake in depressives treated with impramine and ect.抑郁患者接受丙咪嗪和电抽搐治疗后血小板 5-羟色胺摄取的活性
Indian J Psychiatry. 1998 Jan;40(1):60-6.
4
3H-imipramine binding and serotonin uptake in platelets from untreated depressed patients and control volunteers.未治疗的抑郁症患者和对照志愿者血小板中3H-丙咪嗪结合及5-羟色胺摄取情况
Psychopharmacology (Berl). 1982;77(4):332-5. doi: 10.1007/BF00432765.
5
Biochemical assessment of antidepressive drugs.抗抑郁药物的生化评估。
Br J Clin Pharmacol. 1980 Dec;10(6):539-50. doi: 10.1111/j.1365-2125.1980.tb00508.x.
6
5-Hydroxytryptamine (5-HT) in the whole-blood of patients with depressive illness.抑郁症患者全血中的5-羟色胺（5-HT）
Postgrad Med J. 1976 Mar;52(605):156-8. doi: 10.1136/pgmj.52.605.156.
7
The content and uptake of 5-HT by blood platelets in depressive patients.抑郁症患者血小板对5-羟色胺的摄取及其含量
J Neural Transm. 1979;45(4):285-9. doi: 10.1007/BF01247145.
8
Effect of mianserin hydrochloride on peripheral uptake mechanisms for noradrenaline and 5-hydroxytryptamine in man.盐酸米安色林对人体去甲肾上腺素和5-羟色胺外周摄取机制的影响。
Br J Clin Pharmacol. 1978;5 Suppl 1(Suppl 1):13S-17S.
9
Decreased uptake of 5-hydroxytryptamine in blood platelets from patients with endogenous depression.内源性抑郁症患者血小板中5-羟色胺摄取减少。
Psychopharmacology (Berl). 1979 Oct;65(2):141-7. doi: 10.1007/BF00433040.
本文引用的文献
1
Tryptamine metabolism in depression.抑郁症中的色胺代谢
Br J Psychiatry. 1965 Oct;111(479):993-8. doi: 10.1192/bjp.111.479.993.
2
Metabolism, transfer and storage of 5-hydroxytryptamine in blood platelets.5-羟色胺在血小板中的代谢、转运与储存
Br J Pharmacol Chemother. 1968 Jan;32(1):1-16. doi: 10.1111/j.1476-5381.1968.tb00423.x.
Zotero 插件