Borbély A A
Brain Res. 1977 Apr 1;124(3):457-71. doi: 10.1016/0006-8993(77)90947-7.
Continuous telemetric EEG recordings served to determine the vigilance states of the rat during 2 control days, 80 h of food deprivation and 64 h following restitution of food. The recordings were supplemented by measurements of food intake, water intake and motor activity. The following 3 sleep parameters were not significantly changed by food deprivation: the daily amount of the vigilance states, the light-dark distribution of sleep and waking, and the 10 min paradoxical sleep (PS) cycle. During food deprivation, PS was depressed in the dark phase of the diurnal cycle and increased in the light phase. The sleep parameter that was most affected by food deprivation was the duration of sleep episodes. Episodes of slow-wave sleep (SWS) and PS were shortened only in the dark phase of the deprivation days, whereas total sleep episodes were progressively decreased in both diurnal phases. After restitution of food, the episodes of SWS and total sleep were immediately lengthened and tended to exceed the control level. The duration of feeding episodes and meal size were significantly increased in comparison to pre-deprivation values, whereas feeding frequency was decreased. Long episodes of continuous motor activity occurred during the dark phase of the refeeding period, while a fragmented activity pattern was typical for the deprivation nights. It is proposed that the adjustment of the length of behavioral episodes may constitute an important adaptive mechanism for the rat.
连续遥测脑电图记录用于确定大鼠在2个对照日、80小时禁食期和恢复进食后64小时内的警觉状态。记录还补充了食物摄入量、水摄入量和运动活动的测量。以下3个睡眠参数在禁食期间没有显著变化：警觉状态的每日时长、睡眠和清醒的明暗分布以及10分钟快速眼动睡眠（PS）周期。在禁食期间，PS在昼夜周期的黑暗阶段受到抑制，在光照阶段增加。受禁食影响最大的睡眠参数是睡眠片段的持续时间。慢波睡眠（SWS）和PS片段仅在禁食日的黑暗阶段缩短，而总睡眠片段在昼夜两个阶段均逐渐减少。恢复进食后，SWS片段和总睡眠时间立即延长，并趋于超过对照水平。与禁食前的值相比，进食片段的持续时间和每餐食量显著增加，而进食频率降低。在重新进食期的黑暗阶段出现长时间的连续运动活动，而碎片化的活动模式是禁食夜间的典型特征。有人提出，行为片段长度的调整可能是大鼠的一种重要适应性机制。
