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[Effect of lithium chloride on several indices of cardiac function].

作者信息

Stoliarchuk A A, Umanets V S

出版信息

Farmakol Toksikol. 1977 Jan-Feb;40(1):33-6.

PMID:558111
Abstract

Used in a dose of 100 mg/kg lithium chloride modifies the ECG patterns in rats, rabbits and cats. It increases the voltage of P and R waves, the S-T interval and slows down the rhythm of cardiac contractions. In doses of 50-300 mg/kg the compound raises the coronary circulation rate in narcotized cats. The compound exerts an antiarrhythmic action in chlorocalcium arrhythmia in rats, in strophanthin-induced one in cats and frogs and the intensity of this action is not inferior to that produced by potassium chloride, quinidine, novacainamide, izoptin and even exceeds it.

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