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人体红细胞和血红蛋白溶液中的非溶剂水。

Nonsolvent water in human erythrocytes and hemoglobin solutions.

作者信息

Bobo C M

出版信息

J Gen Physiol. 1967 Dec;50(11):2547-64. doi: 10.1085/jgp.50.11.2547.

Abstract

Distribution ratios of water-soluble nonelectrolytes have been measured for two systems, human red bood cells/isotonic saline and hemoglobin solutions/water. The results show that for these solutes there is a significant amount of nonsolvent water associated with Hb. However, the amount of this nonsolvent water depends markedly on the temperature, as well as on the size, steric configuration, and functional groups of the probe solutes. The significance of the data is discussed.

摘要

已测量了两种体系中水溶性非电解质的分配比,即人体红细胞/等渗盐水体系以及血红蛋白溶液/水体系。结果表明,对于这些溶质而言,存在大量与血红蛋白相关的非溶剂水。然而,这种非溶剂水的量显著取决于温度,以及探针溶质的大小、空间构型和官能团。文中讨论了这些数据的意义。

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本文引用的文献

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Solvent water in the mammalian erythrocyte.哺乳动物红细胞中的溶剂水。
J Physiol. 1936 Feb 8;86(2):147-52. doi: 10.1113/jphysiol.1936.sp003349.
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OSMOTIC PROPERTIES OF HUMAN RED CELLS.人类红细胞的渗透特性。
J Gen Physiol. 1964 Sep;48(1):79-94. doi: 10.1085/jgp.48.1.79.
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The redistribution of the red cells on centrifugation.
Acta Haematol. 1960 Feb;23:92-5. doi: 10.1159/000206211.
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Chemistry of proteins, peptides, and amino acids.
Annu Rev Biochem. 1955;24:181-206. doi: 10.1146/annurev.bi.24.070155.001145.
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The behavior of human erythrocytes in aqueous alcohol solutions.
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