Sefton B M
Cell. 1977 Apr;10(4):659-68. doi: 10.1016/0092-8674(77)90099-x.
The mechanism by which the membrane proteins of Sindbis virus are initially glycosylated during growth of the virus in chick cells was studied. The experiments suggest strongly that the two viral glycoproteins are glycosylated before release from the polysome, and that this glycosylation involves transfer of a large 1800 dalton oligosaccharide to the polypeptide chains. The donor of the oligosaccharide is most probably a lipid.
研究了辛德毕斯病毒在鸡细胞中生长时其膜蛋白最初进行糖基化的机制。实验有力地表明，这两种病毒糖蛋白在从多核糖体释放之前就已被糖基化，并且这种糖基化涉及将一个1800道尔顿的大寡糖转移到多肽链上。该寡糖的供体很可能是一种脂质。
