人类肿瘤干细胞的初步生物测定。
Primary bioassay of human tumor stem cells.
作者信息
Hamburger A W, Salmon S E
出版信息
Science. 1977 Jul 29;197(4302):461-3. doi: 10.1126/science.560061.
PMID:560061
Abstract
A simple method has been developed to support human tumor stem cell colony growth in soft agar. The technique appears suitable for culture of a variety of neoplasms of differing histopathology. Tumor stem cell colonies arising from different types of cancer have differing growth characteristics and colony morphology. This bioassay should be suitable for clinical studies of effects of anticancer drugs or irradiation on human tumor stem cells.
摘要
已开发出一种简单方法来支持人肿瘤干细胞集落在软琼脂中生长。该技术似乎适用于培养具有不同组织病理学的多种肿瘤。源自不同类型癌症的肿瘤干细胞集落具有不同的生长特征和集落形态。这种生物测定法应适用于抗癌药物或辐射对人肿瘤干细胞作用的临床研究。
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