Gerendai I, Marchetti B, Maugeri S, Roxas M A, Scapagnini U
Neuroendocrinology. 1978;27(5-6):272-8. doi: 10.1159/000122819.
The possible role of a neural mechanism involved in the development of compensatory ovarian hypertrophy has been studied. A new technique, the use of a special plastic capsule, has been developed to allow chronic local treatment of the ovary. Local treatment of one of the ovaries with 6-hydroxydopamine (6-OHDA) resulted in a weight increase in the other ovary. In the unilaterally ovariectomized rat the local application of 6-OHDA on the ovary blocked the development of compensatory ovarian hypertrophy. Local treatment of the ovary with dopamine (DA) did not interfere with the compensatory ovarian growth of the other ovary. Data suggest that intact adrenergic afferent and efferent neural elements of the ovary are required for the development of compensatory ovarian hypertrophy.
对参与代偿性卵巢肥大发展的神经机制的可能作用进行了研究。已开发出一种新技术，即使用特殊的塑料胶囊，以便对卵巢进行慢性局部治疗。用6-羟基多巴胺（6-OHDA）对一侧卵巢进行局部治疗导致另一侧卵巢重量增加。在单侧卵巢切除的大鼠中，在卵巢上局部应用6-OHDA可阻断代偿性卵巢肥大的发展。用多巴胺（DA）对卵巢进行局部治疗并不干扰另一侧卵巢的代偿性生长。数据表明，卵巢完整的肾上腺素能传入和传出神经元件是代偿性卵巢肥大发展所必需的。
