Solomon F
Cell. 1979 Jan;16(1):165-9. doi: 10.1016/0092-8674(79)90197-1.
Neuroblastoma cells exhibit a wide variety of patterns of neurite morphology. However, when these cells are induced to extend neurites under conditions in which mitotic sister cells are readily identifiable, 60% of these sister pairs display analogous morphologies. These cells are related either as identical twins or as mirror images of each other. The relatedness is expressed in considerable detail of neurite morphology. These relationshiops can persist through at least two cell divisions. The results suggest that animal cells can inherit specific determinants of shape.
神经母细胞瘤细胞表现出多种神经突形态模式。然而,当这些细胞在有丝分裂姐妹细胞易于识别的条件下被诱导伸出神经突时,60%的这些姐妹对表现出相似的形态。这些细胞要么像同卵双胞胎一样相关,要么彼此互为镜像。这种相关性在神经突形态的相当细节中得以体现。这些关系至少可以持续两个细胞分裂。结果表明动物细胞可以继承特定的形状决定因素。