抗淋巴细胞抗体对体液抗体形成影响的进一步研究。

Further studies on the effect of anti-lymphocytic antibody on humoral antibody formation.

作者信息

James K, Pullar D M, James V S

出版信息

Clin Exp Immunol. 1968 Nov;3(9):963-72.

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1579013/

Abstract

The effect of 3-, 6- and 12-day courses of anti-lymphocytic IgG treatment (1 ml of 2 g/100 ml) on the primary humoral response of random bred Wistar rats has been investigated. The primary response to alum precipitated bovine serum albumin was suppressed by all these courses. In contrast however the primary response to sheep erythrocytes was suppressed by the 6-day treatment alone or by a 3-day course augmented with azathioprine treatment. Additional experiments performed in hooded rats confirm that prolonged courses of anti-lymphocytic globulin failed to exert an antidotal effect.

摘要

研究了3天、6天和12天疗程的抗淋巴细胞IgG治疗（1ml，2g/100ml）对随机繁殖的Wistar大鼠初次体液反应的影响。所有这些疗程均抑制了对明矾沉淀牛血清白蛋白的初次反应。然而，相比之下，仅6天的治疗或联合硫唑嘌呤治疗的3天疗程抑制了对绵羊红细胞的初次反应。在有头罩大鼠中进行的额外实验证实，延长疗程的抗淋巴细胞球蛋白未能发挥解毒作用。

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引用本文的文献

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本文引用的文献

1

Preparation of iodine-131 labelled human growth hormone of high specific activity.

Nature. 1962 May 5;194:495-6. doi: 10.1038/194495a0.

2

THE EFFECT OF LYMPHOCYTE DEPLETION BY THORACIC DUCT FISTULA AND ADMINISTRATION OF ANTILYMPHOCYTIC SERUM ON THE SURVIVAL OF SKIN HOMOGRAFTS IN RATS.

Ann N Y Acad Sci. 1964 Nov 30;120:119-28. doi: 10.1111/j.1749-6632.1964.tb34710.x.

3

The attachment of proteins to aldehyde-tanned cells.

Br J Haematol. 1961 Jul;7:299-302. doi: 10.1111/j.1365-2141.1961.tb00340.x.

4

A quantitative immunochemical measure of the primary interaction between I BSA and antibody.

J Infect Dis. 1958 Nov-Dec;103(3):239-62. doi: 10.1093/infdis/103.3.239.

5

Factors influencing the immune response. I. Effects of the physical state of the antigen and of lymphoreticular cell proliferation on the response to intravenous injection of bovine serum albumin in rabbits.

Clin Exp Immunol. 1967 May;2(3):331-41.

6

The preparation and testing of horse antidog and antihuman antilymphoid plasma or serum and its protein fractions.

Surg Gynecol Obstet. 1967 Jan;124(1):1-24.

7

Lymphopenic effect of anti-lymphocyte serum.

Proc Soc Exp Biol Med. 1966 Mar;121(3):722-5. doi: 10.3181/00379727-121-30870.

8

Immune response to anti-lymphocyte globulin.

J Immunol. 1968 Mar;100(3):654-8.

9

Nature and mode of action of antilymphocytic antiserum.

Proc Natl Acad Sci U S A. 1966 Oct;56(4):1130-7. doi: 10.1073/pnas.56.4.1130.

10

Studies on heterologous anti-lymphocyte serum in mice. II. Effect on the immune response.

J Immunol. 1966 Feb;96(2):229-38.

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