James K, Pullar D M, James V S
Clin Exp Immunol. 1968 Nov;3(9):963-72.
The effect of 3-, 6- and 12-day courses of anti-lymphocytic IgG treatment (1 ml of 2 g/100 ml) on the primary humoral response of random bred Wistar rats has been investigated. The primary response to alum precipitated bovine serum albumin was suppressed by all these courses. In contrast however the primary response to sheep erythrocytes was suppressed by the 6-day treatment alone or by a 3-day course augmented with azathioprine treatment. Additional experiments performed in hooded rats confirm that prolonged courses of anti-lymphocytic globulin failed to exert an antidotal effect.
研究了3天、6天和12天疗程的抗淋巴细胞IgG治疗（1ml，2g/100ml）对随机繁殖的Wistar大鼠初次体液反应的影响。所有这些疗程均抑制了对明矾沉淀牛血清白蛋白的初次反应。然而，相比之下，仅6天的治疗或联合硫唑嘌呤治疗的3天疗程抑制了对绵羊红细胞的初次反应。在有头罩大鼠中进行的额外实验证实，延长疗程的抗淋巴细胞球蛋白未能发挥解毒作用。
