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微生物核糖核酸的研究。VI. 酿酒酵母对数生长期甲基缺乏型转移核糖核酸的出现。

Studies on microbial ribonucleic acid. VI. Appearance of methyl-deficient transfer ribonucleic acid during logarithmic growth of Saccharomyces cerevisiae.

作者信息

Kjellin-Stråby K, Phillips J H

出版信息

J Bacteriol. 1968 Sep;96(3):760-7. doi: 10.1128/jb.96.3.760-767.1968.

Abstract

Transfer ribonucleic acid (tRNA) that is deficient in methyl groups may be detected in logarithmically growing Saccharomyces cerevisiae. The amount of methyl-deficient tRNA is not constant throughout the logarithmic phase, but is maximal about one generation before the onset of the late growth phase. During this latter phase, the tRNA is fully methylated. The methyl-deficient tRNA is present during a period of high metabolic activity of the cell, characterized by increased RNA and protein content.

摘要

在对数生长期的酿酒酵母中可能检测到甲基基团缺乏的转运核糖核酸(tRNA)。在整个对数生长期,甲基缺乏的tRNA的量并不恒定,但在生长后期开始前约一代时达到最大值。在生长后期,tRNA会完全甲基化。甲基缺乏的tRNA存在于细胞高代谢活性的时期,其特征是RNA和蛋白质含量增加。

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Characteristics of the methylation in vivo of ribosomal RNA in yeast.酵母核糖体RNA的体内甲基化特征
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本文引用的文献

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SPECIES VARIATION OF THE RNA METHYLASES.RNA甲基化酶的物种变异
Biochemistry. 1964 May;3:616-9. doi: 10.1021/bi00893a003.

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