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1
Studies on microbial ribonucleic acid. VI. Appearance of methyl-deficient transfer ribonucleic acid during logarithmic growth of Saccharomyces cerevisiae.微生物核糖核酸的研究。VI. 酿酒酵母对数生长期甲基缺乏型转移核糖核酸的出现。
J Bacteriol. 1968 Sep;96(3):760-7. doi: 10.1128/jb.96.3.760-767.1968.
2
Methyl-deficient transfer ribonucleic acid in Saccharomyces cerevisiae.酿酒酵母中甲基缺乏的转移核糖核酸
J Bacteriol. 1969 Nov;100(2):695-700. doi: 10.1128/jb.100.2.695-700.1969.
3
Methyl-deficient transfer ribonucleic acid and macromolecular synthesis in methionine-starved Saccharomyces cerevisiae.蛋氨酸饥饿的酿酒酵母中甲基缺乏的转移核糖核酸与大分子合成
J Bacteriol. 1969 Nov;100(2):679-86. doi: 10.1128/jb.100.2.679-686.1969.
4
Influence of methionine pool composition on the formation of methyl-deficient transfer ribonucleic acid in Saccharomyces cerevisiae.甲硫氨酸库组成对酿酒酵母中甲基缺乏型转移核糖核酸形成的影响。
J Bacteriol. 1969 Nov;100(2):687-94. doi: 10.1128/jb.100.2.687-694.1969.
5
Characteristics of the methylation in vivo of ribosomal RNA in yeast.酵母核糖体RNA的体内甲基化特征
Biochim Biophys Acta. 1969 Dec 16;195(2):370-80. doi: 10.1016/0005-2787(69)90643-1.
6
Appearance of a new species of ribonucleic acid during sporulation in Saccharomyces cerevisiae.酿酒酵母孢子形成过程中一种新的核糖核酸物种的出现。
J Bacteriol. 1971 Mar;105(3):826-30. doi: 10.1128/jb.105.3.826-830.1971.
7
Uptake and utilization of S-adenosyl-L-methionine and S-adenosyl-L-homocysteine in an adenine mutant of Saccharomyces cerevisiae.酿酒酵母腺嘌呤突变体中S-腺苷-L-甲硫氨酸和S-腺苷-L-高半胱氨酸的摄取与利用
J Bacteriol. 1969 May;98(2):629-36. doi: 10.1128/jb.98.2.629-636.1969.
8
Methionine-mediated repression in Saccharomyces cerevisiae: a pleiotropic regulatory system involving methionyl transfer ribonucleic acid and the product of gene eth2.酿酒酵母中蛋氨酸介导的阻遏作用：一种涉及甲硫氨酰转移核糖核酸和eth2基因产物的多效调节系统。
J Bacteriol. 1971 Jun;106(3):758-72. doi: 10.1128/jb.106.3.758-772.1971.
9
[A study of the incorporation of 5-fluorouracil into transfer and ribosomal ribonucleic acids of yeast].[关于5-氟尿嘧啶掺入酵母转移核糖核酸和核糖体核糖核酸的研究]
Biochim Biophys Acta. 1969 Jan 21;174(1):43-52.
10
Synthesis of ribonucleic acids during the germination of Rhizopus stolonifer sporangiospores.匍枝根霉孢子囊孢子萌发过程中核糖核酸的合成
Dev Biol. 1974 Nov;41(1):137-45. doi: 10.1016/0012-1606(74)90289-9.

引用本文的文献

1
Methyl-deficient transfer ribonucleic acid in Saccharomyces cerevisiae.酿酒酵母中甲基缺乏的转移核糖核酸
J Bacteriol. 1969 Nov;100(2):695-700. doi: 10.1128/jb.100.2.695-700.1969.
2
Influence of methionine pool composition on the formation of methyl-deficient transfer ribonucleic acid in Saccharomyces cerevisiae.甲硫氨酸库组成对酿酒酵母中甲基缺乏型转移核糖核酸形成的影响。
J Bacteriol. 1969 Nov;100(2):687-94. doi: 10.1128/jb.100.2.687-694.1969.
3
Methyl-deficient transfer ribonucleic acid and macromolecular synthesis in methionine-starved Saccharomyces cerevisiae.蛋氨酸饥饿的酿酒酵母中甲基缺乏的转移核糖核酸与大分子合成
J Bacteriol. 1969 Nov;100(2):679-86. doi: 10.1128/jb.100.2.679-686.1969.
4
Effect of hypermethylation on the functional properties of transfer ribonucleic acid.高甲基化对转移核糖核酸功能特性的影响。
Biochem J. 1969 Sep;114(2):429-35. doi: 10.1042/bj1140429.
5
A mutant of Saccharomyces cerevisiae that exhibits multiple isoacceptors for several of its transfer RNAs.一种酿酒酵母突变体，其几种转移RNA表现出多个同工受体。
Mol Gen Genet. 1977 Jun 8;153(2):145-51. doi: 10.1007/BF00264729.

本文引用的文献

1
A study of the properties of the free amino acid pool and enzyme synthesis in yeast.酵母中游离氨基酸库的性质及酶合成的研究。
J Gen Physiol. 1955 Mar 20;38(4):549-73. doi: 10.1085/jgp.38.4.549.
2
A CELL-FREE AMINO ACID-INCORPORATING SYSTEM FROM SACCHAROMYCES CEREVISIAE. VARIATION IN RIBOSOMAL ACTIVITY AND IN RNA SYNTHESIS DURING LOGARITHMIC GROWTH.来自酿酒酵母的无细胞氨基酸掺入系统。对数生长期间核糖体活性和RNA合成的变化。
Biochemistry. 1964 Jul;3:959-67. doi: 10.1021/bi00895a020.
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SPECIES VARIATION OF THE RNA METHYLASES.RNA甲基化酶的物种变异
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4
STUDIES ON MICROBIAL RNA. I. TRANSFER OF METHYL GROUPS FROM METHIONINE TO SOLUBLE RNA FROM ESCHERICHIA COLI.微生物RNA的研究。I. 甲基基团从甲硫氨酸转移至大肠杆菌的可溶性RNA
J Mol Biol. 1963 Sep;7:254-71. doi: 10.1016/s0022-2836(63)80006-6.
5
"Molecular sieving" of bacterial RNA.细菌RNA的“分子筛”作用
Arch Biochem Biophys. 1962 Sep;Suppl 1:276-82.
6
Regulation of homoserine O-transacetylase, first step in methionine biosyntheis in Saccharomyces cerevisiae.酿酒酵母中甲硫氨酸生物合成第一步——高丝氨酸O-转乙酰酶的调控
Biochem Biophys Res Commun. 1967 Jul 21;28(2):256-62. doi: 10.1016/0006-291x(67)90438-x.
7
Studies on microbial ribonucleic acid. IV. Two mutants of Saccharomyces cerevisiae lacking N-2-dimethylguanine in soluble ribonucleic acid.微生物核糖核酸的研究。IV。酿酒酵母的两个突变体，其可溶性核糖核酸中缺乏N-2-二甲基鸟嘌呤。
J Mol Biol. 1967 Jun 28;26(3):509-18. doi: 10.1016/0022-2836(67)90318-x.
8
[Repression by glucose of alcohol dehydrogenase, malate dehydrogenase, isocitrate lyase and malate synthase in yeast].[葡萄糖对酵母中乙醇脱氢酶、苹果酸脱氢酶、异柠檬酸裂解酶和苹果酸合酶的抑制作用]
Biochim Biophys Acta. 1966 Jun 15;118(3):522-37.
9
Alterations in the transfer ribonucleic acid methylases after bacteriophage infection or induction.噬菌体感染或诱导后转移核糖核酸甲基化酶的变化。
Biochemistry. 1965 Dec;4(12):2845-8. doi: 10.1021/bi00888a040.
10
A new change in leucine transfer RNA observed in Escherichia coli infected with bacteriophage T2.在被噬菌体T2感染的大肠杆菌中观察到的亮氨酸转移核糖核酸的一种新变化。
Proc Natl Acad Sci U S A. 1967 Apr;57(4):979-85. doi: 10.1073/pnas.57.4.979.

微生物核糖核酸的研究。VI. 酿酒酵母对数生长期甲基缺乏型转移核糖核酸的出现。

Studies on microbial ribonucleic acid. VI. Appearance of methyl-deficient transfer ribonucleic acid during logarithmic growth of Saccharomyces cerevisiae.

作者信息

Kjellin-Stråby K, Phillips J H

出版信息

J Bacteriol. 1968 Sep;96(3):760-7. doi: 10.1128/jb.96.3.760-767.1968.

DOI:10.1128/jb.96.3.760-767.1968
PMID:5732508
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC252370/
Abstract

Transfer ribonucleic acid (tRNA) that is deficient in methyl groups may be detected in logarithmically growing Saccharomyces cerevisiae. The amount of methyl-deficient tRNA is not constant throughout the logarithmic phase, but is maximal about one generation before the onset of the late growth phase. During this latter phase, the tRNA is fully methylated. The methyl-deficient tRNA is present during a period of high metabolic activity of the cell, characterized by increased RNA and protein content.

摘要

在对数生长期的酿酒酵母中可能检测到甲基基团缺乏的转运核糖核酸（tRNA）。在整个对数生长期，甲基缺乏的tRNA的量并不恒定，但在生长后期开始前约一代时达到最大值。在生长后期，tRNA会完全甲基化。甲基缺乏的tRNA存在于细胞高代谢活性的时期，其特征是RNA和蛋白质含量增加。