Kistner J R, Longnecker D E, Miller E D, Lescanic A D
Anesth Analg. 1979 Nov-Dec;58(6):457-60. doi: 10.1213/00000539-197911000-00003.
Although the cyanide ion-specific electrode has been used for the measurement of cyanide in biologic fluids, its validity has not been documented under these conditions. Therefore, we analyzed 60 paired samples of blood and plasma in a blinded fashion and compared the cyanide ion concentrations obtained from the ion-specific electrode with those obtained from a standard chemical assay. There was poor correlation between results in plasma samples (r = .52, n = 26) and no correlation in whole blood (r = .02, n = 34). Until refinements of the electrode technique are made, this method cannot be recommended for the measurement of cyanide in biologic fluids.
尽管氰离子特异性电极已用于测量生物体液中的氰化物,但在这些条件下其有效性尚未得到证实。因此,我们以盲法分析了60对血液和血浆样本,并将离子特异性电极测得的氰离子浓度与标准化学分析法测得的浓度进行了比较。血浆样本结果之间的相关性较差(r = 0.52,n = 26),全血中则无相关性(r = 0.02,n = 34)。在电极技术得到改进之前,不推荐使用这种方法测量生物体液中的氰化物。