一种蛙皮素样肽在人胃肠道中的分布。

Distribution of a bombesin-like peptide in human gastrointestinal tract.

作者信息

Polak J M, Bloom S R, Hobbs S, Solcia E, Pearse A G

出版信息

Lancet. 1976 May 22;1(7969):1109-10. doi: 10.1016/s0140-6736(76)90068-4.

Abstract

The bombesin group of hormonal peptides produced in the amphibian skin have powerful actions on the mammalian gastrointestinal tract. In man a bombesin-like material was found in an endocrine cell which is widely distributed in the gastrointestinal mucosa. This has tentatively been identified as belonging to the non-enterochromaffin cell groups. The large number of cells containing a bombesin-like peptide suggests that this substance may be important in human physiology.

摘要

两栖动物皮肤中产生的铃蟾肽类激素肽对哺乳动物胃肠道有强大作用。在人体中，一种类似铃蟾肽的物质在广泛分布于胃肠道黏膜的一种内分泌细胞中被发现。该物质初步被确定属于非肠嗜铬细胞群。大量含有类似铃蟾肽肽的细胞表明这种物质可能在人体生理学中具有重要意义。