一种用于测定血清中布替林的气液色谱法。
A gas-liquid chromatographic method for the determination of butriptyline in serum.
作者信息
Bruderlein H, Kraml M, Dvornik D
出版信息
Clin Biochem. 1977 Feb;10(1):3-7. doi: 10.1016/s0009-9120(77)90058-3.
PMID:576416
Abstract
- A gas-liquid chromatographic (GC) method for the analysis of butriptyline in serum has been development. Quantitation is based on the peak height ratio between butriptyline and promazine used as internal standard. A triple partition provides a "clean" extract. A detection limit of 10 ng/ml is achieved. 2. The usefulness of the method has been demonstrated in bioavailability studies in dogs.
摘要
- 已开发出一种用于分析血清中布替林的气-液色谱（GC）方法。定量基于布替林与用作内标物的丙嗪之间的峰高比。三次分配可提供“纯净”提取物。检测限达到10纳克/毫升。2. 该方法的实用性已在犬的生物利用度研究中得到证实。
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