Zietz E, Spiteller G
Arzneimittelforschung. 1977 Feb;27(2):355-6.
4-Hydroxy-antipyrine, the main metabolite of antipyrine is decomposed in alkaline medium to 2-acetyl-2-methyl-1-phenyl-hydrazine. Consequently this compound is often found in the working up of antipyrine-containing drugs.
4-羟基安替比林是安替比林的主要代谢产物,在碱性介质中分解为2-乙酰基-2-甲基-1-苯基肼。因此,在含安替比林药物的后处理过程中经常会发现这种化合物。