Hladovec J
Arzneimittelforschung. 1977;27(5):1073-6.
A group of vasotropic drugs was surveyed using a new assay method based on the inhibition of endothelaemia increases after a standard vascular lesion in rats. The new test is considerably more sensitive than all previous ones. It provides a common link between all tested vasotropic drugs and points also to their common mechanism of action. All of them have a protective effect on endotherlium based, in some of them at least, on the preservation of the consistency of endothelial cement. The effect is probably mediated by their influence on calcium availability.
利用一种基于抑制大鼠标准血管损伤后内皮血症增加的新检测方法，对一组血管亲和性药物进行了研究。这种新检测方法比以往所有方法都要灵敏得多。它揭示了所有受试血管亲和性药物之间的共同联系，也指出了它们共同的作用机制。所有这些药物都对内皮有保护作用，至少其中一些药物是基于保持内皮黏附物质的完整性。这种作用可能是由它们对钙可用性的影响介导的。
