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马拉松跑步II:对血小板聚集的影响。

Marathon run II: Effects on platelet aggregation.

作者信息

Dimitriadou C, Dessypris A, Louizou C, Mandalaki T

出版信息

Thromb Haemost. 1977 Jun 30;37(3):451-5.

PMID:578025
Abstract

Platelet count and aggregation were assessed in 9 Finnish amateur runners aged 34 to 48, and one 65-year old taking part in a non-competitive marathon race (42.2 km). After the run the mean value of platelet count showed a very significant rise (p less than 0.001). The platelets were markedly more sensitive to both ADP and collagen-induced aggregation. A highly significant increase (p less than 0.001) was noted for both the intensity and velocity of platelet aggregation. The finding of platelet by hyperaggregability after prolonged strenous exercise even in trained subjects is discussed. It is concluded that a through medical examination of the haemostatic balance is recommended before a marathon race.

摘要

对9名年龄在34至48岁的芬兰业余跑步者以及一名参加非竞争性马拉松比赛(42.2公里)的65岁老人进行了血小板计数和聚集性评估。跑步后,血小板计数的平均值出现了非常显著的升高(p<0.001)。血小板对ADP和胶原诱导的聚集明显更敏感。血小板聚集的强度和速度均出现了高度显著的增加(p<0.001)。本文讨论了即使在训练有素的受试者中,长时间剧烈运动后血小板出现高聚集性的这一发现。得出的结论是,建议在马拉松比赛前对止血平衡进行全面的医学检查。

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